Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P09211 GSTP1 Glutathione S-transferase P (EC 2.5.1.18) … Homo sapiens (Human) 210 aa

Protein Details: P09211 (GSTP1)

Protein Information
AccessionP09211
Protein NamesGlutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1)
Gene SymbolGSTP1
OrganismHomo sapiens (Human)
Length210 aa
IsoformsNo isoforms
Related PMIDs 21076176 29575903 29733200 31382980 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPPYTVVYFP11VRGRCAALRM21LLADQGQSWK31EEVVTVETWQ41EGSLKASCLY
51-10051GQLPKFQDGD61LTLYQSNTIL71RHLGRTLGLY81GKDQQEAALV91DMVNDGVEDL
101-150101RCKYISLIYT111NYEAGKDDYV121KALPGQLKPF131ETLLSQNQGG141KTFIVGDQIS
151-200151FADYNLLDLL161LIHEVLAPGC171LDAFPLLSAY181VGRLSARPKL191KAFLASPEYV
201-210201NLPINGNGKQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
15 Glutathione S-transferase, N-terminal Thioredoxin-like superfamily Glutaredoxin - -
GPS-Palm: 0.87
Deep-Palm: 0.93
48 SWISSPALM DBPTM CYSMODDB Glutathione S-transferase, N-terminal Thioredoxin-like superfamily Glutaredoxin -
Unknown (32651440)
cerebral cortex (36430497)
GPS-Palm: 0.84
Deep-Palm: 0.98
102 - - -
Deep-Palm: 0.67
170 - - -
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
cerebral cortex
Specificity: 0.286
4/4 (100.0%)
2
HAP1 cell
Specificity: 0.143
2/2 (100.0%)
1
U937 cell
Specificity: 0.071
1/1 (100.0%)
1
HeLa cell
Specificity: 0.071
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.071
1/1 (100.0%)
1
293T cell
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.286
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
71 R → C 0.002020 SNP Missense Mutation PRAD
183 R → C 0.001887 SNP Missense Mutation UCEC