Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P09382 | LGALS1 | Galectin-1 (Gal-1) (14 kDa laminin-binding … | Homo sapiens (Human) | 135 aa |
Protein Details: P09382 (LGALS1)
Protein Information
| Accession | P09382 |
|---|---|
| Protein Names | Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1) |
| Gene Symbol | LGALS1 |
| Organism | Homo sapiens (Human) |
| Length | 135 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MACGLVASNL11NLKPGECLRV21RGEVAPDAKS31FVLNLGKDSN41NLCLHFNPRF
51-10051NAHGDANTIV61CNSKDGGAWG71TEQREAVFPF81QPGSVAEVCI91TFDQANLTVK
101-135101LPDGYEFKFP111NRLNLEAINY121MAADGDFKIK131CVAFD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.97
Deep-Palm: 0.04
|
| 17 | SWISSPALM DBPTM CYSMODDB | Galectin, carbohydrate recognition domain Concanavalin A-like lectin/glucanase domain superfamily |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.90
Deep-Palm: 0.98
|
| 43 | SWISSPALM DBPTM CYSMODDB | Concanavalin A-like lectin/glucanase domain superfamily Galectin, carbohydrate recognition domain Galactoside-binding lectin |
HeLa
(29575903)
| - |
GPS-Palm: 0.73
Deep-Palm: 0.88
|
| 61 | SWISSPALM DBPTM CYSMODDB | Galactoside-binding lectin |
SW480 cell line
(26865113)
|
cerebral cortex
(36430497)
|
Deep-Palm: 0.48
|
| 89 | - | - | - |
Deep-Palm: 0.73
|
|
| 131 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
1
HAP1 cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.444
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 43 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |