Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P09972 | ALDOC | Fructose-bisphosphate aldolase C (EC 4.1.2.13) … | Homo sapiens (Human) | 364 aa |
Protein Details: P09972 (ALDOC)
Protein Information
| Accession | P09972 |
|---|---|
| Protein Names | Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) |
| Gene Symbol | ALDOC |
| Organism | Homo sapiens (Human) |
| Length | 364 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPHSYPALSA11EQKKELSDIA21LRIVAPGKGI31LAADESVGSM41AKRLSQIGVE
51-10051NTEENRRLYR61QVLFSADDRV71KKCIGGVIFF81HETLYQKDDN91GVPFVRTIQD
101-150101KGIVVGIKVD111KGVVPLAGTD121GETTTQGLDG131LSERCAQYKK141DGADFAKWRC
151-200151VLKISERTPS161ALAILENANV171LARYASICQQ181NGIVPIVEPE191ILPDGDHDLK
201-250201RCQYVTEKVL211AAVYKALSDH221HVYLEGTLLK231PNMVTPGHAC241PIKYTPEEIA
251-300251MATVTALRRT261VPPAVPGVTF271LSGGQSEEEA281SFNLNAINRC291PLPRPWALTF
301-350301SYGRALQASA311LNAWRGQRDN321AGAATEEFIK331RAEVNGLAAQ341GKYEGSGEDG
351-364351GAAAQSLYIA361NHAY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 73 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.79
Deep-Palm: 0.45
|
|
| 135 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.91
|
|
| 150 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.92
|
|
| 178 | SWISSPALM DBPTM CYSMODDB | Fructose-bisphosphate aldolase class-I |
HeLa
(29575903)
|
Unknown
(32651440)
cerebral cortex
(36430497)
|
GPS-Palm: 0.87
Deep-Palm: 0.90
|
| 202 | - | - | - |
Deep-Palm: 0.96
|
|
| 240 | - | - | - |
Deep-Palm: 0.86
|
|
| 290 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.77
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
cerebral cortex
Specificity: 0.286
4/4 (100.0%)
3
PC3
Specificity: 0.214
3/3 (100.0%)
2
LNCaP
Specificity: 0.143
2/2 (100.0%)
1
heart
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.286
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 69 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 173 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 240 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 304 | R → C | 0.002294 | SNP | Missense Mutation | OV |