Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P09972 | ALDOC; ALDC | Fructose-bisphosphate aldolase C (EC 4.1.2.13) … | Homo sapiens (Human) | 364 aa |
Protein Details: P09972 (ALDOC)
Protein Information
| Accession | P09972 |
|---|---|
| Protein Names | Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) |
| Gene Symbol | ALDOC; ALDC |
| Organism | Homo sapiens (Human) |
| Length | 364 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 31251020 32944167 33636221 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.762
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
32
LNCaP cells
Specificity: 0.762
32/46 (69.6%)
4
Cerebral cortex
Specificity: 0.095
4/4 (100.0%)
3
PC3 cells
Specificity: 0.071
3/4 (75.0%)
2
Jurkat T cells
Specificity: 0.048
2/25 (8.0%)
1
Liver membrane
Specificity: 0.024
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPHSYPALSA11EQKKELSDIA21LRIVAPGKGI31LAADESVGSM41AKRLSQIGVE
51-10051NTEENRRLYR61QVLFSADDRV71KKCIGGVIFF81HETLYQKDDN91GVPFVRTIQD
101-150101KGIVVGIKVD111KGVVPLAGTD121GETTTQGLDG131LSERCAQYKK141DGADFAKWRC
151-200151VLKISERTPS161ALAILENANV171LARYASICQQ181NGIVPIVEPE191ILPDGDHDLK
201-250201RCQYVTEKVL211AAVYKALSDH221HVYLEGTLLK231PNMVTPGHAC241PIKYTPEEIA
251-300251MATVTALRRT261VPPAVPGVTF271LSGGQSEEEA281SFNLNAINRC291PLPRPWALTF
301-350301SYGRALQASA311LNAWRGQRDN321AGAATEEFIK331RAEVNGLAAQ341GKYEGSGEDG
351-364351GAAAQSLYIA361NHAY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 73 | Prediction (Medium) | - | - |
| 135 | Prediction (Low) | - | - |
| 150 | Prediction (Low) | - | - |
| 178 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Fructose-bisphosphate aldolase class-I | - |
| 290 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 69 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 173 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 240 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 304 | R → C | 0.002294 | SNP | Missense Mutation | OV |