Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P10114 | RAP2A | Ras-related protein Rap-2a (EC 3.6.5.2) … | Homo sapiens (Human) | 183 aa |
Protein Details: P10114 (RAP2A)
Protein Information
| Accession | P10114 |
|---|---|
| Protein Names | Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30) |
| Gene Symbol | RAP2A |
| Organism | Homo sapiens (Human) |
| Length | 183 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 24357059 26111759 26876311 29733200 31251020 31382980 33636221 36430497 |
| Database Sources | dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.510
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.510
25/46 (54.3%)
6
Jurkat T cells
Specificity: 0.122
6/25 (24.0%)
4
T cells
Specificity: 0.082
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.082
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.082
4/4 (100.0%)
2
DU145 cells
Specificity: 0.041
2/2 (100.0%)
1
U937 cells
Specificity: 0.020
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.020
1/2 (50.0%)
1
Prefrontal cortex
Specificity: 0.020
1/1 (100.0%)
1
Liver membrane
Specificity: 0.020
1/1 (100.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MREYKVVVLG11SGGVGKSALT21VQFVTGTFIE31KYDPTIEDFY41RKEIEVDSSP
51-10051SVLEILDTAG61TEQFASMRDL71YIKNGQGFIL81VYSLVNQQSF91QDIKPMRDQI
101-150101IRVKRYEKVP111VILVGNKVDL121ESEREVSSSE131GRALAEEWGC141PFMETSAKSK
151-183151TMVDELFAEI161VRQMNYAAQP171DKDDPCCSAC181NIQ
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 140 | Prediction (Low) | - | - |
| 176 | DBPTM SWISSPALM Prediction (Low) | - | - |
| 177 | DBPTM SWISSPALM Prediction (Medium) | - | - |
| 180 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 140 | C → F | 0.002288 | SNP | Missense Mutation | STAD |