Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P10126 Eef1a1 Elongation factor 1-alpha 1 (EF-1-alpha-1) … Mus musculus (Mouse) 462 aa

Protein Details: P10126 (Eef1a1)

Protein Information
AccessionP10126
Protein NamesElongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1)
Gene SymbolEef1a1
OrganismMus musculus (Mouse)
Length462 aa
IsoformsNo isoforms
Related PMIDs 28526873 29575903 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGKEKTHINI11VVIGHVDSGK21STTTGHLIYK31CGGIDKRTIE41KFEKEAAEMG
51-10051KGSFKYAWVL61DKLKAERERG71ITIDISLWKF81ETSKYYVTII91DAPGHRDFIK
101-150101NMITGTSQAD111CAVLIVAAGV121GEFEAGISKN131GQTREHALLA141YTLGVKQLIV
151-200151GVNKMDSTEP161PYSQKRYEEI171VKEVSTYIKK181IGYNPDTVAF191VPISGWNGDN
201-250201MLEPSANMPW211FKGWKVTRKD221GSASGTTLLE231ALDCILPPTR241PTDKPLRLPL
251-300251QDVYKIGGIG261TVPVGRVETG271VLKPGMVVTF281APVNVTTEVK291SVEMHHEALS
301-350301EALPGDNVGF311NVKNVSVKDV321RRGNVAGDSK331NDPPMEAAGF341TAQVIILNHP
351-400351GQISAGYAPV361LDCHTAHIAC371KFAELKEKID381RRSGKKLEDG391PKFLKSGDAA
401-450401IVDMVPGKPM411CVESFSDYPP421LGRFAVRDMR431QTVAVGVIKA441VDKKAAGAGK
451-462451VTKSAQKAQK461AK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
31 Translational (tr)-type GTP-binding domain P-loop containing nucleoside triphosphate hydrolase Translation factor GTPase superfamily members - -
GPS-Palm: 0.68
Deep-Palm: 0.96
111 - -
Brain (35358180)
GPS-Palm: 0.73
Deep-Palm: 0.92
234 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
Forebrain (28680068)
Liver (37925639)
Brain (35358180)
Macrophage Raw 264.7 (29217618)
Brain (31311849)
Deep-Palm: 0.98
363 - - -
Deep-Palm: 0.79
370 - - -
Deep-Palm: 0.90
411 SWISSPALM DBPTM CYSMODDB GTP-eEF1A C-terminal domain-like
Liver (28526873)
NSC (31772009)
Brain (35358180)
Deep-Palm: 0.64
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.107
6/6 (100.0%)
4
Brain
Specificity: 0.071
4/4 (100.0%)
2
Testis
Specificity: 0.036
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.018
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.791
34
Brain tissue (Mass)
Specificity: 0.607
34/56 (60.7%)
9
Macrophage Raw 264.7 (Mass)
Specificity: 0.161
9/10 (90.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine