Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P10276 | RARA | Retinoic acid receptor alpha (RAR-alpha) … | Homo sapiens (Human) | 462 aa |
Protein Details: P10276 (RARA)
Protein Information
| Accession | P10276 |
|---|---|
| Protein Names | Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1) |
| Gene Symbol | RARA |
| Organism | Homo sapiens (Human) |
| Length | 462 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASNSSSCPT11PGGGHLNGYP21VPPYAFFFPP31MLGGLSPPGA41LTTLQHQLPV
51-10051SGYSTPSPAT61IETQSSSSEE71IVPSPPSPPP81LPRIYKPCFV91CQDKSSGYHY
101-150101GVSACEGCKG111FFRRSIQKNM121VYTCHRDKNC131IINKVTRNRC141QYCRLQKCFE
151-200151VGMSKESVRN161DRNKKKKEVP171KPECSESYTL181TPEVGELIEK191VRKAHQETFP
201-250201ALCQLGKYTT211NNSSEQRVSL221DIDLWDKFSE231LSTKCIIKTV241EFAKQLPGFT
251-300251TLTIADQITL261LKAACLDILI271LRICTRYTPE281QDTMTFSDGL291TLNRTQMHNA
301-350301GFGPLTDLVF311AFANQLLPLE321MDDAETGLLS331AICLICGDRQ341DLEQPDRVDM
351-400351LQEPLLEALK361VYVRKRRPSR371PHMFPKMLMK381ITDLRSISAK391GAERVITLKM
401-450401EIPGSMPPLI411QEMLENSEGL421DTLSGQPGGG431GRDGGGLAPP441PGSCSPSLSP
451-462451SSNRSSPATH461SP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | - | - | - |
Deep-Palm: 0.02
|
|
| 88 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.22
|
|
| 91 | - | - | - |
Deep-Palm: 0.17
|
|
| 105 | DBPTM SWISSPALM | Double treble clef zinc finger C4 type | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.18
|
| 108 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.23
|
|
| 124 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.08
|
|
| 130 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.02
|
|
| 140 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.03
|
|
| 143 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.07
|
|
| 148 | - | - | - |
Deep-Palm: 0.10
|
|
| 174 | DBPTM SWISSPALM | - | - | - |
Deep-Palm: 0.94
|
| 203 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.95
|
|
| 235 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.93
|
|
| 265 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.94
|
|
| 274 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.89
|
|
| 333 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.78
|
|
| 336 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.72
|
|
| 444 | - | - | - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 91 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 108 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 122 | Y → C | 0.002545 | SNP | Missense Mutation | GBM |
| 143 | C → C | 0.001764 | SNP | Silent | LUAD |
| 174 | C → S | 0.002033 | SNP | Missense Mutation | LUSC |
| 192 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 217 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |