Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P10605 | Ctsb | Cathepsin B (EC 3.4.22.1) (Cathepsin … | Mus musculus (Mouse) | 339 aa |
Protein Details: P10605 (Ctsb)
Protein Information
| Accession | P10605 |
|---|---|
| Protein Names | Cathepsin B (EC 3.4.22.1) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] |
| Gene Symbol | Ctsb |
| Organism | Mus musculus (Mouse) |
| Length | 339 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29575903 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MWWSLILLSC11LLALTSAHDK21PSFHPLSDDL31INYINKQNTT41WQAGRNFYNV
51-10051DISYLKKLCG61TVLGGPKLPG71RVAFGEDIDL81PETFDAREQW91SNCPTIGQIR
101-150101DQGSCGSCWA111FGAVEAISDR121TCIHTNGRVN131VEVSAEDLLT141CCGIQCGDGC
151-200151NGGYPSGAWS161FWTKKGLVSG171GVYNSHVGCL181PYTIPPCEHH191VNGSRPPCTG
201-250201EGDTPRCNKS211CEAGYSPSYK221EDKHFGYTSY231SVSNSVKEIM241AEIYKNGPVE
251-300251GAFTVFSDFL261TYKSGVYKHE271AGDMMGGHAI281RILGWGVENG291VPYWLAANSW
301-339301NLDWGDNGFF311KILRGENHCG321IESEIVAGIP331RTDQYWGRF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.03
|
|
| 59 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.96
|
|
| 93 | SWISSPALM DBPTM CYSMODDB | Papain family cysteine protease |
liver
(26165157)
brain
(39008777)
MLE
(39008777)
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.88
Deep-Palm: 0.39
|
| 105 | - |
brain
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.08
|
|
| 108 | - |
brain
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.14
|
|
| 122 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.46
|
|
| 141 | - | - | - |
Deep-Palm: 0.76
|
|
| 142 | - | - | - |
Deep-Palm: 0.81
|
|
| 146 | - | - | - |
Deep-Palm: 0.58
|
|
| 150 | - | - | - |
Deep-Palm: 0.17
|
|
| 179 | - | - | - |
Deep-Palm: 0.62
|
|
| 187 | - | - | - |
Deep-Palm: 0.08
|
|
| 198 | - | - | - |
Deep-Palm: 0.08
|
|
| 207 | - | - | - |
Deep-Palm: 0.13
|
|
| 211 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.25
|
| 319 | SWISSPALM DBPTM CYSMODDB | Papain family cysteine protease |
liver
(26165157)
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.82
Deep-Palm: 0.62
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.136
6/6 (100.0%)
4
Brain
Specificity: 0.091
4/4 (100.0%)
2
Testis
Specificity: 0.045
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.023
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
31
Brain tissue (Mass)
Specificity: 0.705
31/56 (55.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.