Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P10643 C7 Complement component C7 Homo sapiens (Human) 843 aa

Protein Details: P10643 (C7)

Protein Information
Accession P10643
Protein Names Complement component C7
Gene Symbol C7
Organism Homo sapiens (Human)
Length 843 aa
Isoforms No isoforms
Related PMIDs 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Liver membrane
Specificity: 1.000
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKVISLFILV11GFIGEFQSFS21SASSPVNCQW31DFYAPWSECN41GCTKTQTRRR
51-10051SVAVYGQYGG61QPCVGNAFET71QSCEPTRGCP81TEEGCGERFR91CFSGQCISKS
101-150101LVCNGDSDCD111EDSADEDRCE121DSERRPSCDI131DKPPPNIELT141GNGYNELTGQ
151-200151FRNRVINTKS161FGGQCRKVFS171GDGKDFYRLS181GNVLSYTFQV191KINNDFNYEF
201-250201YNSTWSYVKH211TSTEHTSSSR221KRSFFRSSSS231SSRSYTSHTN241EIHKGKSYQL
251-300251LVVENTVEVA261QFINNNPEFL271QLAEPFWKEL281SHLPSLYDYS291AYRRLIDQYG
301-350301THYLQSGSLG311GEYRVLFYVD321SEKLKQNDFN331SVEEKKCKSS341GWHFVVKFSS
351-400351HGCKELENAL361KAASGTQNNV371LRGEPFIRGG381GAGFISGLSY391LELDNPAGNK
401-450401RRYSAWAESV411TNLPQVIKQK421LTPLYELVKE431VPCASVKKLY441LKWALEEYLD
451-500451EFDPCHCRPC461QNGGLATVEG471THCLCHCKPY481TFGAACEQGV491LVGNQAGGVD
501-550501GGWSCWSSWS511PCVQGKKTRS521RECNNPPPSG531GGRSCVGETT541ESTQCEDEEL
551-600551EHLRLLEPHC561FPLSLVPTEF571CPSPPALKDG581FVQDEGTMFP591VGKNVVYTCN
601-650601EGYSLIGNPV611ARCGEDLRWL621VGEMHCQKIA631CVLPVLMDGI641QSHPQKPFYT
651-700651VGEKVTVSCS661GGMSLEGPSA671FLCGSSLKWS681PEMKNARCVQ691KENPLTQAVP
701-750701KCQRWEKLQN711SRCVCKMPYE721CGPSLDVCAQ731DERSKRILPL741TVCKMHVLHC
751-800751QGRNYTLTGR761DSCTLPASAE771KACGACPLWG781KCDAESSKCV791CREASECEEE
801-843801GFSICVEVNG811KEQTMSECEA821GALRCRGQSI831SVTSIRPCAA841ETQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
42 Prediction (Medium) - -
96 Prediction (Low) - -
165 Prediction (Low) - -
353 Prediction (Low) - -
433 Prediction (Medium) - -
512 Prediction (Low) - -
613 Prediction (Low) - -
702 Prediction (Medium) - -
728 Prediction (Low) - -
743 Prediction (Medium) - -
750 Prediction (Low) - -
763 Prediction (Low) - -
773 Prediction (Low) - -
818 Prediction (Low) - -
838 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
218 S → C 0.001887 SNP Missense Mutation UCEC
222 R → C 0.002545 SNP Missense Mutation GBM
306 S → C 0.005435 SNP Missense Mutation ESCA
406 W → C 0.002033 SNP Missense Mutation LUSC
473 C → R 0.002141 SNP Missense Mutation SKCM
512 C → F 0.002033 SNP Missense Mutation LUSC
534 S → C 0.002033 SNP Missense Mutation LUSC
571 C → C 0.002506 SNP Silent COAD
659 C → S 0.003527 SNP Missense Mutation LUAD
671 F → C 0.001969 SNP Missense Mutation HNSC
679 W → C 0.001014 SNP Missense Mutation BRCA
702 C → Y 0.002294 SNP Missense Mutation OV
713 C → R 0.002294 SNP Missense Mutation OV
773 C → R 0.002141 SNP Missense Mutation SKCM
803 S → C 0.002747 SNP Missense Mutation LIHC
626* C → ? 0.017544 SNP Nonsense Mutation UCS