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UniProt ID Gene Symbol Protein Name Organism Length Action
P10966 CD8B T-cell surface glycoprotein CD8 beta … Homo sapiens (Human) 210 aa

Protein Details: P10966 (CD8B)

Protein Information
AccessionP10966
Protein NamesT-cell surface glycoprotein CD8 beta chain (CD antigen CD8b)
Gene SymbolCD8B
OrganismHomo sapiens (Human)
Length210 aa
IsoformsNo isoforms
Related PMIDs 24357059
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRPRLWLLLA11AQLTVLHGNS21VLQQTPAYIK31VQTNKMVMLS41CEAKISLSNM
51-10051RIYWLRQRQA61PSSDSHHEFL71ALWDSAKGTI81HGEEVEQEKI91AVFRDASRFI
101-150101LNLTSVKPED111SGIYFCMIVG121SPELTFGKGT131QLSVVDFLPT141TAQPTKKSTL
151-200151KKRVCRLPRP161ETQKGPLCSP171ITLGLLVAGV181LVLLVSLGVA191IHLCCRRRRA
201-210201RLRFMKQFYK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
41 - - -
Deep-Palm: 0.33
116 - - -
Deep-Palm: 0.54
155 - - -
Deep-Palm: 0.95
168 - - -
Deep-Palm: 0.98
194 DBPTM SWISSPALM - - -
Deep-Palm: 0.98
195 DBPTM SWISSPALM - - -
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
HUVECs
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
221 C → F 0.002294 SNP Missense Mutation OV