Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P11049 | CD37 | Leukocyte antigen CD37 (Tetraspanin-26) (Tspan-26) … | Homo sapiens (Human) | 281 aa |
Protein Details: P11049 (CD37)
Protein Information
| Accession | P11049 |
|---|---|
| Protein Names | Leukocyte antigen CD37 (Tetraspanin-26) (Tspan-26) (CD antigen CD37) |
| Gene Symbol | CD37 |
| Organism | Homo sapiens (Human) |
| Length | 281 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 26111759 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSAQESCLSL11IKYFLFVFNL21FFFVLGSLIF31CFGIWILIDK41TSFVSFVGLA
51-10051FVPLQIWSKV61LAISGIFTMG71IALLGCVGAL81KELRCLLGLY91FGMLLLLFAT
101-150101QITLGILIST111QRAQLERSLR121DVVEKTIQKY131GTNPEETAAE141ESWDYVQFQL
151-200151RCCGWHYPQD161WFQVLILRGN171GSEAHRVPCS181CYNLSATNDS191TILDKVILPQ
201-250201LSRLGHLARS211RHSADICAVP221AESHIYREGC231AQGLQKWLHN241NLISIVGICL
251-281251GVGLLELGFM261TLSIFLCRNL271DHVYNRLARY281R
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.01
|
|
| 31 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.07
|
|
| 76 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.98
|
|
| 85 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.98
|
|
| 152 | - | - | - |
Deep-Palm: 0.50
|
|
| 153 | - | - | - |
Deep-Palm: 0.56
|
|
| 179 | - | - | - |
Deep-Palm: 0.38
|
|
| 181 | - | - | - |
Deep-Palm: 0.35
|
|
| 217 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.71
|
|
| 230 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.73
|
|
| 249 | - | - | - |
Deep-Palm: 0.90
|
|
| 267 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Primary T cell
Specificity: 0.667
4/4 (100.0%)
2
CEM 174 cell
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 20 | L → _F21insC | 0.002288 | INS | In Frame Ins | STAD |
| 153 | C → F | 0.002506 | SNP | Missense Mutation | COAD |
| 217 | C → C | 0.001887 | SNP | Silent | UCEC |
| 249* | C → ? | 0.002545 | SNP | Nonsense Mutation | GBM |