Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P11166 | SLC2A1 | Solute carrier family 2, facilitated … | Homo sapiens (Human) | 492 aa |
Protein Details: P11166 (SLC2A1)
Protein Information
| Accession | P11166 |
|---|---|
| Protein Names | Solute carrier family 2, facilitated glucose transporter member 1 (Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (HepG2 glucose transporter) |
| Gene Symbol | SLC2A1 |
| Organism | Homo sapiens (Human) |
| Length | 492 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 31251020 31382980 |
| Database Sources | PTMDSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEPSSKKLTG11RLMLAVGGAV21LGSLQFGYNT31GVINAPQKVI41EEFYNQTWVH
51-10051RYGESILPTT61LTTLWSLSVA71IFSVGGMIGS81FSVGLFVNRF91GRRNSMLMMN
101-150101LLAFVSAVLM111GFSKLGKSFE121MLILGRFIIG131VYCGLTTGFV141PMYVGEVSPT
151-200151ALRGALGTLH161QLGIVVGILI171AQVFGLDSIM181GNKDLWPLLL191SIIFIPALLQ
201-250201CIVLPFCPES211PRFLLINRNE221ENRAKSVLKK231LRGTADVTHD241LQEMKEESRQ
251-300251MMREKKVTIL261ELFRSPAYRQ271PILIAVVLQL281SQQLSGINAV291FYYSTSIFEK
301-350301AGVQQPVYAT311IGSGIVNTAF321TVVSLFVVER331AGRRTLHLIG341LAGMAGCAIL
351-400351MTIALALLEQ361LPWMSYLSIV371AIFGFVAFFE381VGPGPIPWFI391VAELFSQGPR
401-450401PAAIAVAGFS411NWTSNFIVGM421CFQYVEQLCG431PYVFIIFTVL441LVLFFIFTYF
451-492451KVPETKGRTF461DEIASGFRQG471GASQSDKTPE481ELFHPLGADS491QV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 133 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.42
|
|
| 201 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.92
|
|
| 207 | PTMD SWISSPALM | Sugar (and other) transporter | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.80
|
| 347 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.91
|
|
| 421 | - | - | - |
Deep-Palm: 0.04
|
|
| 429 | - | - | - |
Deep-Palm: 0.10
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
LNCaP
Specificity: 0.500
2/2 (100.0%)
1
U937 cell
Specificity: 0.250
1/1 (100.0%)
1
frontal cortex
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 44 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 51 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 89 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 111 | G → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 201 | C → C | 0.001887 | SNP | Silent | UCEC |
| 232 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 232 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |