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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P11352 Gpx1 Glutathione peroxidase 1 (GPx-1) (GSHPx-1) … Mus musculus (Mouse) 201 aa

Protein Details: P11352 (Gpx1)

Protein Information
AccessionP11352
Protein NamesGlutathione peroxidase 1 (GPx-1) (GSHPx-1) (EC 1.11.1.9) (Cellular glutathione peroxidase) (Phospholipid-hydroperoxide glutathione peroxidase GPX1) (EC 1.11.1.12) (Selenium-dependent glutathione peroxidase 1)
Gene SymbolGpx1
OrganismMus musculus (Mouse)
Length201 aa
IsoformsNo isoforms
Related PMIDs 28526873 34200797 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MCAARLSAAA11QSTVYAFSAR21PLTGGEPVSL31GSLRGKVLLI41ENVASLUGTT
51-10051IRDYTEMNDL61QKRLGPRGLV71VLGFPCNQFG81HQENGKNEEI91LNSLKYVRPG
101-150101GGFEPNFTLF111EKCEVNGEKA121HPLFTFLRNA131LPTPSDDPTA141LMTDPKYIIW
151-200151SPVCRNDIAW161NFEKFLVGPD171GVPVRRYSRR181FRTIDIEPDI191ETLLSQQSGN
201-201201S
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
2 - - -
GPS-Palm: 0.95
Deep-Palm: 0.04
76 SWISSPALM DBPTM CYSMODDB Glutathione peroxidase
liver (26165157)
brain (39008777)
Liver (28526873)
Liver (34884899)
Brain (35358180)
GPS-Palm: 0.87
Deep-Palm: 0.97
113 - - -
Deep-Palm: 0.93
154 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.89
Deep-Palm: 0.20
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
6
Liver
Specificity: 0.286
6/6 (100.0%)
2
Brain
Specificity: 0.095
2/2 (100.0%)
2
Testis
Specificity: 0.095
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.818
9
Brain tissue (Mass)
Specificity: 0.429
9/56 (16.1%)
2
Liver tissue (Mass)
Specificity: 0.095
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine