Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P11499 | Hsp90ab1 | Heat shock protein HSP 90-beta … | Mus musculus (Mouse) | 724 aa |
Protein Details: P11499 (Hsp90ab1)
Protein Information
| Accession | P11499 |
|---|---|
| Protein Names | Heat shock protein HSP 90-beta (Heat shock 84 kDa) (HSP 84) (HSP84) (Tumor-specific transplantation 84 kDa antigen) (TSTA) |
| Gene Symbol | Hsp90ab1 |
| Organism | Mus musculus (Mouse) |
| Length | 724 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPEEVHHGEE11EVETFAFQAE21IAQLMSLIIN31TFYSNKEIFL41RELISNASDA
51-10051LDKIRYESLT61DPSKLDSGKE71LKIDIIPNPQ81ERTLTLVDTG91IGMTKADLIN
101-150101NLGTIAKSGT111KAFMEALQAG121ADISMIGQFG131VGFYSAYLVA141EKVVVITKHN
151-200151DDEQYAWESS161AGGSFTVRAD171HGEPIGRGTK181VILHLKEDQT191EYLEERRVKE
201-250201VVKKHSQFIG211YPITLYLEKE221REKEISDDEA231EEEKGEKEEE241DKEDEEKPKI
251-300251EDVGSDEEDD261SGKDKKKKTK271KIKEKYIDQE281ELNKTKPIWT291RNPDDITQEE
301-350301YGEFYKSLTN311DWEDHLAVKH321FSVEGQLEFR331ALLFIPRRAP341FDLFENKKKK
351-400351NNIKLYVRRV361FIMDSCDELI371PEYLNFIRGV381VDSEDLPLNI391SREMLQQSKI
401-450401LKVIRKNIVK411KCLELFSELA421EDKENYKKFY431EAFSKNLKLG441IHEDSTNRRR
451-500451LSELLRYHTS461QSGDEMTSLS471EYVSRMKETQ481KSIYYITGES491KEQVANSAFV
501-550501ERVRKRGFEV511VYMTEPIDEY521CVQQLKEFDG531KSLVSVTKEG541LELPEDEEEK
551-600551KKMEESKAKF561ENLCKLMKEI571LDKKVEKVTI581SNRLVSSPCC591IVTSTYGWTA
601-650601NMERIMKAQA611LRDNSTMGYM621MAKKHLEINP631DHPIVETLRQ641KAEADKNDKA
651-700651VKDLVVLLFE661TALLSSGFSL671EDPQTHSNRI681YRMIKLGLGI691DEDEVTAEEP
701-724701SAAVPDEIPP711LEGDEDASRM721EEVD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 366 | - | - |
Liver
(34884899)
NSC
(31772009)
Brain
(35358180)
|
GPS-Palm: 0.71
Deep-Palm: 0.54
|
|
| 412 | SWISSPALM DBPTM CYSMODDB | Hsp90 protein |
liver
(26165157)
|
Brain
(31311849)
|
GPS-Palm: 0.81
Deep-Palm: 0.96
|
| 521 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.75
|
|
| 564 | SWISSPALM DBPTM CYSMODDB | Hsp90 protein |
liver
(26165157)
MLE
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.89
Deep-Palm: 0.97
|
| 589 | Hsp90 protein |
Brain
(34200797)
MLE
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.88
Deep-Palm: 0.81
|
|
| 590 | Hsp90 protein |
MLE
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.83
Deep-Palm: 0.83
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.147
5/5 (100.0%)
3
Brain
Specificity: 0.088
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
26
Brain tissue (Mass)
Specificity: 0.765
26/56 (46.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.