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UniProt ID Gene Symbol Protein Name Organism Length Action
P11686 SFTPC Surfactant protein C (SP-C) (Pulmonary … Homo sapiens (Human) 197 aa

Protein Details: P11686 (SFTPC)

Protein Information
AccessionP11686
Protein NamesSurfactant protein C (SP-C) (Pulmonary surfactant-associated protein C) (Pulmonary surfactant-associated proteolipid SPL(Val)) (SP5)
Gene SymbolSFTPC
OrganismHomo sapiens (Human)
Length197 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDVGSKEVLM11ESPPDYSAAP21RGRFGIPCCP31VHLKRLLIVV41VVVVLIVVVI
51-10051VGALLMGLHM61SQKHTEMVLE71MSIGAPEAQQ81RLALSEHLVT91TATFSIGSTG
101-150101LVVYDYQQLL111IAYKPAPGTC121CYIMKIAPES131IPSLEALTRK141VHNFQMECSL
151-197151QAKPAVPTSK161LGQAEGRDAG171SAPSGGDPAF181LGMAVSTLCG191EVPLYYI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
28 DBPTM SWISSPALM Surfactant protein C N terminal propeptide Surfactant-associated polypeptide, palmitoylation site Surfactant protein C, N-terminal propeptide Pulmonary surfactant-associated protein C - -
GPS-Palm: 0.97
Deep-Palm: 0.98
29 DBPTM SWISSPALM Surfactant protein C N terminal propeptide Pulmonary surfactant-associated protein C Surfactant protein C, N-terminal propeptide - -
GPS-Palm: 0.96
Deep-Palm: 0.98
120 - - -
GPS-Palm: 0.86
Deep-Palm: 0.61
121 - - -
GPS-Palm: 0.79
Deep-Palm: 0.68
148 - - -
GPS-Palm: 0.68
Deep-Palm: 0.92
189 - - -
Deep-Palm: 0.11
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
35 R → C 0.002545 SNP Missense Mutation GBM
35 R → C 0.001887 SNP Missense Mutation UCEC