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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P11714 Cyp2d9 Cytochrome P450 2D9 (EC 1.14.14.1) … Mus musculus (Mouse) 504 aa

Protein Details: P11714 (Cyp2d9)

Protein Information
AccessionP11714
Protein NamesCytochrome P450 2D9 (EC 1.14.14.1) (CYPIID9) (Cytochrome P450-16-alpha) (Cytochrome P450CA) (Testosterone 16-alpha hydroxylase)
Gene SymbolCyp2d9
OrganismMus musculus (Mouse)
Length504 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MELLTGTDLW11PVAIFTVIFI21LLVDLTHQRQ31RWTSRYPPGP41VPWPVLGNLL
51-10051QVDLGNMPYS61LYKLQNRYGD71VFSLQMAWKP81MVVINGLKAM91KEMLLTCGED
101-150101TADRPPVPIF111EYLGVKPGSQ121GVVLAPYGPE131WREQRRFSVS141TLRNFGLGKK
151-200151SLEDWVTKEA161NHLCDAFTAQ171AGQPINPNPM181LNKSTCNVIA191SLIFARRFEY
201-250201EDPFLIRMLK211VLEQSLTEVS221GLIPEVLNAF231PILLRIPRLA241DKALQGQKSF
251-300251IAILDNLLTE261NRTTWDPVQA271PRNLTDAFLA281EIEKAKGNPE291SSFNDENLLM
301-350301VVRDLFGAGM311LTTSTTLSWA321LMLMILHPDV331QRRVQQEIDE341VIGQVRHPEM
351-400351ADQAHMPYTN361AVIHEVQRFG371DIVPVNLPRI381TSHDIEVQDF391LIPKGTILLP
401-450401NMSSMLKDES411VWEKPLRFHP421EHFLDAQGHF431VKPEAFMPFS441AGRRSCLGEA
451-500451LARMELFLFF461TCLLQRFSFS471VPDGQPQPSN481SGVYGILVAP491SPYQLCAVVR
501-504501DQGH
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
97 - - -
Deep-Palm: 0.96
164 SWISSPALM DBPTM CYSMODDB Cytochrome P450
Liver (28526873)
-
Deep-Palm: 0.66
186 SWISSPALM DBPTM CYSMODDB Cytochrome P450
Liver (28526873)
liver (26165157)
-
Deep-Palm: 0.79
446 SWISSPALM DBPTM CYSMODDB Cytochrome P450
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.97
462 - - -
Deep-Palm: 0.97
496 - - -
Deep-Palm: 0.04
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine