Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P11836 | MS4A1 | B-lymphocyte antigen CD20 (B-lymphocyte surface … | Homo sapiens (Human) | 297 aa |
Protein Details: P11836 (MS4A1)
Protein Information
| Accession | P11836 |
|---|---|
| Protein Names | B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Bp35) (Leukocyte surface antigen Leu-16) (Membrane-spanning 4-domains subfamily A member 1) (CD antigen CD20) |
| Gene Symbol | MS4A1 |
| Organism | Homo sapiens (Human) |
| Length | 297 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 26111759 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTTPRNSVNG11TFPAEPMKGP21IAMQSGPKPL31FRRMSSLVGP41TQSFFMRESK
51-10051TLGAVQIMNG61LFHIALGGLL71MIPAGIYAPI81CVTVWYPLWG91GIMYIISGSL
101-150101LAATEKNSRK111CLVKGKMIMN121SLSLFAAISG131MILSIMDILN141IKISHFLKME
151-200151SLNFIRAHTP161YINIYNCEPA171NPSEKNSPST181QYCYSIQSLF191LGILSVMLIF
201-250201AFFQELVIAG211IVENEWKRTC221SRPKSNIVLL231SAEEKKEQTI241EIKEEVVGLT
251-297251ETSSQPKNEE261DIEIIPIQEE271EEEETETNFP281EPPQDQESSP291IENDSSP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 81 | - | - | - |
Deep-Palm: 0.75
|
|
| 111 | DBPTM SWISSPALM | CD20-like family | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.96
|
| 167 | - | - | - |
Deep-Palm: 0.04
|
|
| 183 | - | - | - |
Deep-Palm: 0.58
|
|
| 220 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
Primary T cell
Specificity: 0.571
4/4 (100.0%)
3
CEM 174 cell
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 25 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 26 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 81 | C → Y | 0.001969 | SNP | Missense Mutation | LGG |
| 146 | F → C | 0.007299 | SNP | Missense Mutation | READ |
| 154 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |