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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P12235 SLC25A4; AAC1; ANT1 ADP/ATP translocase 1 (ADP,ATP carrier … Homo sapiens (Human) 298 aa

Protein Details: P12235 (SLC25A4)

Protein Information
Accession P12235
Protein Names ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4)
Gene Symbol SLC25A4; AAC1; ANT1
Organism Homo sapiens (Human)
Length 298 aa
Isoforms No isoforms
Related PMIDs 21076176 29733200 31251020 32944167 33636221
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.444
24/46 (52.2%)
10
HAP1 cells
Specificity: 0.185
10/10 (100.0%)
10
293T cells
Specificity: 0.185
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.111
6/25 (24.0%)
3
PC3 cells
Specificity: 0.056
3/4 (75.0%)
1
Liver membrane
Specificity: 0.019
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGDHAWSFLK11DFLAGGVAAA21VSKTAVAPIE31RVKLLLQVQH41ASKQISAEKQ
51-10051YKGIIDCVVR61IPKEQGFLSF71WRGNLANVIR81YFPTQALNFA91FKDKYKQLFL
101-150101GGVDRHKQFW111RYFAGNLASG121GAAGATSLCF131VYPLDFARTR141LAADVGKGAA
151-200151QREFHGLGDC161IIKIFKSDGL171RGLYQGFNVS181VQGIIIYRAA191YFGVYDTAKG
201-250201MLPDPKNVHI211FVSWMIAQSV221TAVAGLVSYP231FDTVRRRMMM241QSGRKGADIM
251-298251YTGTVDCWRK261IAKDEGAKAF271FKGAWSNVLR281GMGGAFVLVL291YDEIKKYV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
57 Prediction (Medium) - -
129 Prediction (Medium) - -
160 Prediction (Medium) - -
257 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
16 G → C 0.001887 SNP Missense Mutation UCEC
71 W → C 0.002294 SNP Missense Mutation OV
80 R → C 0.001014 SNP Missense Mutation BRCA
80 R → C 0.001887 SNP Missense Mutation UCEC
235 R → C 0.001887 SNP Missense Mutation UCEC
129* C → ? 0.002506 SNP Nonsense Mutation COAD