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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P12236 SLC25A6 ADP/ATP translocase 3 (ADP,ATP carrier … Homo sapiens (Human) 298 aa

Protein Details: P12236 (SLC25A6)

Protein Information
AccessionP12236
Protein NamesADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]
Gene SymbolSLC25A6
OrganismHomo sapiens (Human)
Length298 aa
IsoformsNo isoforms
Related PMIDs 19137006 21076176 29733200 31251020 31382980 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTEQAISFAK11DFLAGGIAAA21ISKTAVAPIE31RVKLLLQVQH41ASKQIAADKQ
51-10051YKGIVDCIVR61IPKEQGVLSF71WRGNLANVIR81YFPTQALNFA91FKDKYKQIFL
101-150101GGVDKHTQFW111RYFAGNLASG121GAAGATSLCF131VYPLDFARTR141LAADVGKSGT
151-200151EREFRGLGDC161LVKITKSDGI171RGLYQGFSVS181VQGIIIYRAA191YFGVYDTAKG
201-250201MLPDPKNTHI211VVSWMIAQTV221TAVAGVVSYP231FDTVRRRMMM241QSGRKGADIM
251-298251YTGTVDCWRK261IFRDEGGKAF271FKGAWSNVLR281GMGGAFVLVL291YDELKKVI
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
57 - -
LNCaP (31251020)
cerebral cortex (36430497)
GPS-Palm: 0.87
Deep-Palm: 0.97
129 - -
Unknown (32651440)
GPS-Palm: 0.78
Deep-Palm: 0.98
160 SWISSPALM DBPTM CYSMODDB Mitochondrial carrier protein -
cerebral cortex (36430497)
GPS-Palm: 0.88
Deep-Palm: 0.98
257 - -
LNCaP (31251020)
cerebral cortex (36430497)
GPS-Palm: 0.83
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.250
4
cerebral cortex
Specificity: 0.190
4/4 (100.0%)
3
LNCaP
Specificity: 0.143
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.095
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.095
2/2 (100.0%)
2
PC3
Specificity: 0.095
2/2 (100.0%)
2
293T cell
Specificity: 0.095
2/2 (100.0%)
1
U937 cell
Specificity: 0.048
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Cerebral Cortex (Mass)
Specificity: 0.190
4/4 (100.0%)
1
LNCaP cells (Mass)
Specificity: 0.048
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine