Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P12277 CKB Creatine kinase B-type (EC 2.7.3.2) … Homo sapiens (Human) 381 aa

Protein Details: P12277 (CKB)

Protein Information
AccessionP12277
Protein NamesCreatine kinase B-type (EC 2.7.3.2) (Brain creatine kinase) (B-CK) (Creatine kinase B chain) (Creatine phosphokinase B-type) (CPK-B)
Gene SymbolCKB
OrganismHomo sapiens (Human)
Length381 aa
IsoformsNo isoforms
Related PMIDs 29733200 31251020 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPFSNSHNAL11KLRFPAEDEF21PDLSAHNNHM31AKVLTPELYA41ELRAKSTPSG
51-10051FTLDDVIQTG61VDNPGHPYIM71TVGCVAGDEE81SYEVFKDLFD91PIIEDRHGGY
101-150101KPSDEHKTDL111NPDNLQGGDD121LDPNYVLSSR131VRTGRSIRGF141CLPPHCSRGE
151-200151RRAIEKLAVE161ALSSLDGDLA171GRYYALKSMT181EAEQQQLIDD191HFLFDKPVSP
201-250201LLLASGMARD211WPDARGIWHN221DNKTFLVWVN231EEDHLRVISM241QKGGNMKEVF
251-300251TRFCTGLTQI261ETLFKSKDYE271FMWNPHLGYI281LTCPSNLGTG291LRAGVHIKLP
301-350301NLGKHEKFSE311VLKRLRLQKR321GTGGVDTAAV331GGVFDVSNAD341RLGFSEVELV
351-381351QMVVDGVKLL361IEMEQRLEQG371QAIDDLMPAQ381K
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
74 - - -
Deep-Palm: 0.38
141 - -
cerebral cortex (36430497)
GPS-Palm: 0.95
Deep-Palm: 0.94
146 - -
cerebral cortex (36430497)
GPS-Palm: 0.95
Deep-Palm: 0.95
254 SWISSPALM DBPTM CYSMODDB ATP:guanido phosphotransferase C-terminal catalytic domain
HeLa (29575903)
cerebral cortex (36430497)
GPS-Palm: 0.83
Deep-Palm: 0.94
283 - - -
GPS-Palm: 0.68
Deep-Palm: 0.76
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
cerebral cortex
Specificity: 0.308
4/4 (100.0%)
2
LNCaP
Specificity: 0.154
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.077
1/1 (100.0%)
1
293T cell
Specificity: 0.077
1/1 (100.0%)
1
heart
Specificity: 0.077
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.308
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine