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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P13439 Umps Uridine 5'-monophosphate synthase (UMP synthase) … Mus musculus (Mouse) 481 aa

Protein Details: P13439 (Umps)

Protein Information
AccessionP13439
Protein NamesUridine 5'-monophosphate synthase (UMP synthase) [Includes: Orotate phosphoribosyltransferase (OPRTase) (EC 2.4.2.10); Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) (OMPdecase)]
Gene SymbolUmps
OrganismMus musculus (Mouse)
Length481 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEVASQALGP11LVTELYDVQA21FKFGSFVLKS31GLSSPVYIDL41RGIVSRPRLL
51-10051SQVADILFQT61AKNAGISFDS71VCGVPYTALP81LATVICSANH91IPMLIRRKET
101-150101KDYGTKRLVE111GEINPGQTCL121VIEDVVTSGA131SVLETVEVLQ141KEGLKVTDAI
151-200151VLLDREQGGK161DKLQAQGIRL171HAVCTLSQML181EILQQQEKID191ADMVGRVKRF
201-250201IQENVFSAAN211HNGLPPPEKK221ACKELSFGAR231AELPGTHPLA241SKLLRLMQKK
251-300251ETNLCLSADV261SEARELLQLA271DALGPSICML281KTHVDILNDF291TLDVMEELTA
301-350301LAKRHEFLIF311EDRKFADIGN321TVKKQYESGT331FKIASWADIV341NAHVVPGSGV
351-400351VKGLQEVGLP361LHRACLLIAE371MSSAGSLATG381NYTKAAVGMA391EEHCEFVIGF
401-450401ISGSRVSMKP411EFLHLTPGVQ421LETGGDHLGQ431QYNSPQEVIG441KRGSDVIIVG
451-481451RGILAAANRL461EAAEMYRKAA471WEAYLSRLAV481Q
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
72 - - -
GPS-Palm: 0.69
Deep-Palm: 0.94
86 - - -
Deep-Palm: 0.93
119 - - -
Deep-Palm: 0.97
174 - - -
GPS-Palm: 0.77
Deep-Palm: 0.96
222 - - -
GPS-Palm: 0.71
Deep-Palm: 0.95
255 - - -
GPS-Palm: 0.71
Deep-Palm: 0.98
278 SWISSPALM DBPTM CYSMODDB Orotidine 5'-phosphate decarboxylase / HUMPS family
Liver (28526873)
-
GPS-Palm: 0.75
Deep-Palm: 0.97
365 - - -
GPS-Palm: 0.69
Deep-Palm: 0.98
394 - - -
Deep-Palm: 0.58
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine