Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P13645 KRT10; KPP Keratin, type I cytoskeletal 10 … Homo sapiens (Human) 584 aa

Protein Details: P13645 (KRT10)

Protein Information
Accession P13645
Protein Names Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)
Gene Symbol KRT10; KPP
Organism Homo sapiens (Human)
Length 584 aa
Isoforms No isoforms
Related PMIDs 25914232 29733200 31382980 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.556
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
10
HAP1 cells
Specificity: 0.556
10/10 (100.0%)
4
PC3 cells
Specificity: 0.222
4/4 (100.0%)
3
CEMx174 cells
Specificity: 0.167
3/3 (100.0%)
1
U937 cells
Specificity: 0.056
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSVRYSSSKH11YSSSRSGGGG21GGGGCGGGGG31VSSLRISSSK41GSLGGGFSSG
51-10051GFSGGSFSRG61SSGGGCFGGS71SGGYGGLGGF81GGGSFRGSYG91SSSFGGSYGG
101-150101IFGGGSFGGG111SFGGGSFGGG121GFGGGGFGGG131FGGGFGGDGG141LLSGNEKVTM
151-200151QNLNDRLASY161LDKVRALEES171NYELEGKIKE181WYEKHGNSHQ191GEPRDYSKYY
201-250201KTIDDLKNQI211LNLTTDNANI221LLQIDNARLA231ADDFRLKYEN241EVALRQSVEA
251-300251DINGLRRVLD261ELTLTKADLE271MQIESLTEEL281AYLKKNHEEE291MKDLRNVSTG
301-350301DVNVEMNAAP311GVDLTQLLNN321MRSQYEQLAE331QNRKDAEAWF341NEKSKELTTE
351-400351IDNNIEQISS361YKSEITELRR371NVQALEIELQ381SQLALKQSLE391ASLAETEGRY
401-450401CVQLSQIQAQ411ISALEEQLQQ421IRAETECQNT431EYQQLLDIKI441RLENEIQTYR
451-500451SLLEGEGSSG461GGGRGGGSFG471GGYGGGSSGG481GSSGGGHGGG491HGGSSGGGYG
501-550501GGSSGGGSSG511GGYGGGSSSG521GHGGSSSGGY531GGGSSGGGGG541GYGGGSSGGG
551-584551SSSGGGYGGG561SSSGGHKSSS571SGSVGESSSK581GPRY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
25 Prediction (Medium) - -
66 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
15 R → C 0.002141 SNP Missense Mutation SKCM
44 G → C 0.001887 SNP Missense Mutation UCEC
56 S → C 0.003460 SNP Missense Mutation CESC
83 G → C 0.002545 SNP Missense Mutation GBM
86 R → C 0.002141 SNP Missense Mutation SKCM
94 F → C 0.001887 SNP Missense Mutation UCEC
200 Y → C 0.002506 SNP Missense Mutation COAD
256 R → C 0.005435 SNP Missense Mutation ESCA
399 R → C 0.002020 SNP Missense Mutation PRAD
562 S → C 0.002427 SNP Missense Mutation BLCA
584 Y → C 0.002033 SNP Missense Mutation LUSC