Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P13928 | ANXA8 | Annexin A8 (Annexin VIII) (Annexin-8) … | Homo sapiens (Human) | 327 aa |
Protein Details: P13928 (ANXA8)
Protein Information
| Accession | P13928 |
|---|---|
| Protein Names | Annexin A8 (Annexin VIII) (Annexin-8) (Vascular anticoagulant-beta) (VAC-beta) |
| Gene Symbol | ANXA8 |
| Organism | Homo sapiens (Human) |
| Length | 327 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAWWKSWIEQ11EGVTVKSSSH21FNPDPDAETL31YKAMKGIGTN41EQAIIDVLTK
51-10051RSNTQRQQIA61KSFKAQFGKD71LTETLKSELS81GKFERLIVAL91MYPPYRYEAK
101-150101ELHDAMKGLG111TKEGVIIEIL121ASRTKNQLRE131IMKAYEEDYG141SSLEEDIQAD
151-200151TSGYLERILV161CLLQGSRDDV171SSFVDPGLAL181QDAQDLYAAG191EKIRGTDEMK
201-250201FITILCTRSA211THLLRVFEEY221EKIANKSIED231SIKSETHGSL241EEAMLTVVKC
251-300251TQNLHSYFAE261RLYYAMKGAG271TRDGTLIRNI281VSRSEIDLNL291IKCHFKKMYG
301-327301KTLSSMIMED311TSGDYKNALL321SLVGSDP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 161 | SWISSPALM DBPTM CYSMODDB | Annexin | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.89
|
| 206 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.96
|
|
| 250 | - | - | - |
Deep-Palm: 0.71
|
|
| 293 | - | - | - |
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 194 | R → C | 0.005013 | SNP | Missense Mutation | COAD |
| 208 | R → C | 0.005013 | SNP | Missense Mutation | COAD |
| 208 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |