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UniProt ID Gene Symbol Protein Name Organism Length Action
P14174 MIF Macrophage migration inhibitory factor (MIF) … Homo sapiens (Human) 115 aa

Protein Details: P14174 (MIF)

Protein Information
AccessionP14174
Protein NamesMacrophage migration inhibitory factor (MIF) (EC 5.3.2.1) (Glycosylation-inhibiting factor) (GIF) (L-dopachrome isomerase) (L-dopachrome tautomerase) (EC 5.3.3.12) (Phenylpyruvate tautomerase)
Gene SymbolMIF
OrganismHomo sapiens (Human)
Length115 aa
IsoformsNo isoforms
Related PMIDs 25914232 31251020
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPMFIVNTNV11PRASVPDGFL21SELTQQLAQA31TGKPPQYIAV41HVVPDQLMAF
51-10051GGSSEPCALC61SLHSIGKIGG71AQNRSYSKLL81CGLLAERLRI91SPDRVYINYY
101-115101DMNAANVGWN111NSTFA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
57 - - -
GPS-Palm: 0.73
Deep-Palm: 0.86
60 - - -
Deep-Palm: 0.80
81 SWISSPALM DBPTM CYSMODDB Macrophage migration inhibitory factor (MIF)
SW480 cell line (26865113)
HeLa (29575903)
Unknown (32651440)
GPS-Palm: 0.94
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
CEM 174 cell
Specificity: 0.750
3/3 (100.0%)
1
LNCaP
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine