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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P14550 AKR1A1; ALDR1; ALR Aldo-keto reductase family 1 member … Homo sapiens (Human) 325 aa

Protein Details: P14550 (AKR1A1)

Protein Information
Accession P14550
Protein Names Aldo-keto reductase family 1 member A1 (EC 1.1.1.2) (EC 1.1.1.372) (EC 1.1.1.54) (Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (EC 1.1.1.19) (Glucuronolactone reductase) (EC 1.1.1.20) (S-nitroso-CoA reductase) (ScorR) (EC 1.6.-.-)
Gene Symbol AKR1A1; ALDR1; ALR
Organism Homo sapiens (Human)
Length 325 aa
Isoforms No isoforms
Related PMIDs 29733200 31251020 31382980 32944167 36430497
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.688
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
22
LNCaP cells
Specificity: 0.688
22/46 (47.8%)
4
293T cells
Specificity: 0.125
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.125
4/4 (100.0%)
1
U937 cells
Specificity: 0.031
1/1 (100.0%)
1
PC3 cells
Specificity: 0.031
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAASCVLLHT11GQKMPLIGLG21TWKSEPGQVK31AAVKYALSVG41YRHIDCAAIY
51-10051GNEPEIGEAL61KEDVGPGKAV71PREELFVTSK81LWNTKHHPED91VEPALRKTLA
101-150101DLQLEYLDLY111LMHWPYAFER121GDNPFPKNAD131GTICYDSTHY141KETWKALEAL
151-200151VAKGLVQALG161LSNFNSRQID171DILSVASVRP181AVLQVECHPY191LAQNELIAHC
201-250201QARGLEVTAY211SPLGSSDRAW221RDPDEPVLLE231EPVVLALAEK241YGRSPAQILL
251-300251RWQVQRKVIC261IPKSITPSRI271LQNIKVFDFT281FSPEEMKQLN291ALNKNWRYIV
301-325301PMLTVDGKRV311PRDAGHPLYP321FNDPY
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
5 Prediction (High) - -
260 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
211 S → C 0.001014 SNP Missense Mutation BRCA