Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P14672 | SLC2A4 | Solute carrier family 2, facilitated … | Homo sapiens (Human) | 509 aa |
Protein Details: P14672 (SLC2A4)
Protein Information
| Accession | P14672 |
|---|---|
| Protein Names | Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4) |
| Gene Symbol | SLC2A4 |
| Organism | Homo sapiens (Human) |
| Length | 509 aa |
| Isoforms | No isoforms |
| Related PMIDs | 33636221 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPSGFQQIGS11EDGEPPQQRV21TGTLVLAVFS31AVLGSLQFGY41NIGVINAPQK
51-10051VIEQSYNETW61LGRQGPEGPS71SIPPGTLTTL81WALSVAIFSV91GGMISSFLIG
101-150101IISQWLGRKR111AMLVNNVLAV121LGGSLMGLAN131AAASYEMLIL141GRFLIGAYSG
151-200151LTSGLVPMYV161GEIAPTHLRG171ALGTLNQLAI181VIGILIAQVL191GLESLLGTAS
201-250201LWPLLLGLTV211LPALLQLVLL221PFCPESPRYL231YIIQNLEGPA241RKSLKRLTGW
251-300251ADVSGVLAEL261KDEKRKLERE271RPLSLLQLLG281SRTHRQPLII291AVVLQLSQQL
301-350301SGINAVFYYS311TSIFETAGVG321QPAYATIGAG331VVNTVFTLVS341VLLVERAGRR
351-400351TLHLLGLAGM361CGCAILMTVA371LLLLERVPAM381SYVSIVAIFG391FVAFFEIGPG
401-450401PIPWFIVAEL411FSQGPRPAAM421AVAGFSNWTS431NFIIGMGFQY441VAEAMGPYVF
451-500451LLFAVLLLGF461FIFTFLRVPE471TRGRTFDQIS481AAFHRTPSLL491EQEVKPSTEL
501-509501EYLGPDEND
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 223 | DBPTM SWISSPALM | Sugar (and other) transporter | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.98
|
| 361 | - | - | - |
Deep-Palm: 0.98
|
|
| 363 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
heart
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 282 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 301 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 349 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 394 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |