Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P15105 Glul Glutamine synthetase (GS) (EC 6.3.1.2) … Mus musculus (Mouse) 373 aa

Protein Details: P15105 (Glul)

Protein Information
AccessionP15105
Protein NamesGlutamine synthetase (GS) (EC 6.3.1.2) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL) (EC 2.3.1.225)
Gene SymbolGlul
OrganismMus musculus (Mouse)
Length373 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MATSASSHLN11KGIKQMYMSL21PQGEKVQAMY31IWVDGTGEGL41RCKTRTLDCE
51-10051PKCVEELPEW61NFDGSSTFQS71EGSNSDMYLH81PVAMFRDPFR91KDPNKLVLCE
101-150101VFKYNRKPAE111TNLRHICKRI121MDMVSNQHPW131FGMEQEYTLM141GTDGHPFGWP
151-200151SNGFPGPQGP161YYCGVGADKA171YGRDIVEAHY181RACLYAGVKI191TGTNAEVMPA
201-250201QWEFQIGPCE211GIRMGDHLWI221ARFILHRVCE231DFGVIATFDP241KPIPGNWNGA
251-300251GCHTNFSTKA261MREENGLKCI271EEAIDKLSKR281HQYHIRAYDP291KGGLDNARRL
301-350301TGFHETSNIN311DFSAGVANRG321ASIRIPRTVG331QEKKGYFEDR341RPSANCDPYA
351-373351VTEAIVRTCL361LNETGDEPFQ371YKN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
42 Glutamine Synthetase Glutamine synthetase, N-terminal domain superfamily Glutamine synthetase, N-terminal domain - -
GPS-Palm: 0.65
Deep-Palm: 0.56
49 Glutamine synthetase, N-terminal domain superfamily Glutamine Synthetase Glutamine synthetase, N-terminal domain
brain (39008777)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.70
Deep-Palm: 0.70
53 - - -
Deep-Palm: 0.34
99 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.96
Deep-Palm: 0.91
117 - - -
GPS-Palm: 0.67
Deep-Palm: 0.17
163 - - -
Deep-Palm: 0.75
183 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
liver (26165157)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.87
Deep-Palm: 0.94
209 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Liver (34884899)
Brain (35358180)
GPS-Palm: 0.71
Deep-Palm: 0.30
229 - -
Liver (34884899)
Brain (35358180)
GPS-Palm: 0.77
Deep-Palm: 0.40
252 - - -
Deep-Palm: 0.42
269 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
liver (26165157)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.89
Deep-Palm: 0.85
346 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
liver (26165157)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.92
359 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
Liver (34884899)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.77
Deep-Palm: 0.47
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.111
6/6 (100.0%)
5
Brain
Specificity: 0.093
5/5 (100.0%)
2
Testis
Specificity: 0.037
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
41
Brain tissue (Mass)
Specificity: 0.759
41/56 (73.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine