Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P15153 | RAC2 | Ras-related C3 botulinum toxin substrate … | Homo sapiens (Human) | 192 aa |
Protein Details: P15153 (RAC2)
Protein Information
| Accession | P15153 |
|---|---|
| Protein Names | Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2) |
| Gene Symbol | RAC2 |
| Organism | Homo sapiens (Human) |
| Length | 192 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 29733200 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.706
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.706
24/46 (52.2%)
6
293T cells
Specificity: 0.176
6/10 (60.0%)
4
Jurkat T cells
Specificity: 0.118
4/25 (16.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MQAIKCVVVG11DGAVGKTCLL21ISYTTNAFPG31EYIPTVFDNY41SANVMVDSKP
51-10051VNLGLWDTAG61QEDYDRLRPL71SYPQTDVFLI81CFSLVSPASY91ENVRAKWFPE
101-150101VRHHCPSTPI111ILVGTKLDLR121DDKDTIEKLK131EKKLAPITYP141QGLALAKEID
151-192151SVKYLECSAL161TQRGLKTVFD171EAIRAVLCPQ181PTRQQKRACS191LL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 6 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Ras family | - |
| 18 | Prediction (Low) | - | - |
| 157 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 178 | Prediction (High) | - | - |
| 189 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 18 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 89 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 189 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |