Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P15328 | FOLR1 | Folate receptor alpha (FR-alpha) (Adult … | Homo sapiens (Human) | 257 aa |
Protein Details: P15328 (FOLR1)
Protein Information
| Accession | P15328 |
|---|---|
| Protein Names | Folate receptor alpha (FR-alpha) (Adult folate-binding protein) (FBP) (Folate receptor 1) (Folate receptor, adult) (KB cells FBP) (Ovarian tumor-associated antigen MOv18) |
| Gene Symbol | FOLR1 |
| Organism | Homo sapiens (Human) |
| Length | 257 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAQRMTTQLL11LLLVWVAVVG21EAQTRIAWAR31TELLNVCMNA41KHHKEKPGPE
51-10051DKLHEQCRPW61RKNACCSTNT71SQEAHKDVSY81LYRFNWNHCG91EMAPACKRHF
101-150101IQDTCLYECS111PNLGPWIQQV121DQSWRKERVL131NVPLCKEDCE141QWWEDCRTSY
151-200151TCKSNWHKGW161NWTSGFNKCA171VGAACQPFHF181YFPTPTVLCN191EIWTHSYKVS
201-250201NYSRGSGRCI211QMWFDPAQGN221PNEEVARFYA231AAMSGAGPWA241AWPFLLSLAL
251-257251MLLWLLS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 37 | Folate receptor | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.86
|
|
| 57 | - | - | - |
Deep-Palm: 0.12
|
|
| 65 | - | - | - |
Deep-Palm: 0.18
|
|
| 66 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.17
|
|
| 89 | - | - | - |
Deep-Palm: 0.08
|
|
| 96 | - | - | - |
Deep-Palm: 0.05
|
|
| 105 | - | - | - |
Deep-Palm: 0.08
|
|
| 109 | - | - | - |
Deep-Palm: 0.05
|
|
| 135 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.27
|
|
| 139 | - | - | - |
Deep-Palm: 0.07
|
|
| 146 | - | - | - |
Deep-Palm: 0.03
|
|
| 152 | - | - | - |
Deep-Palm: 0.02
|
|
| 169 | - | - | - |
Deep-Palm: 0.03
|
|
| 175 | - | - | - |
Deep-Palm: 0.05
|
|
| 189 | SWISSPALM DBPTM CYSMODDB | Folate receptor family |
HeLa
(29575903)
| - |
Deep-Palm: 0.08
|
| 209 | - | - | - |
Deep-Palm: 0.13
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 57 | C → S | 0.002545 | SNP | Missense Mutation | GBM |
| 88 | H → delinsLMPLRCSN | 0.001014 | INS | In Frame Ins | BRCA |
| 96 | C → S | 0.019608 | SNP | Missense Mutation | CHOL |
| 169 | C → C | 0.002288 | SNP | Silent | STAD |
| 96* | C → ? | 0.007299 | SNP | Nonsense Mutation | READ |