Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P15392 Cyp2a4 Cytochrome P450 2A4 (EC 1.14.14.1) … Mus musculus (Mouse) 494 aa

Protein Details: P15392 (Cyp2a4)

Protein Information
AccessionP15392
Protein NamesCytochrome P450 2A4 (EC 1.14.14.1) (CYPIIA4) (Cytochrome P450-15-alpha) (Cytochrome P450-IIA3.1) (Testosterone 15-alpha-hydroxylase)
Gene SymbolCyp2a4
OrganismMus musculus (Mouse)
Length494 aa
IsoformsNo isoforms
Related PMIDs 28526873 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLTSGLLLVA11AVAFLSVLVL21MSVWKQRKLS31GKLPPGPTPL41PFVGNFLQLN
51-10051TEQMYNSLMK61ISQRYGPVFT71IYLGSRRIVV81LCGQETVKEA91LVDQAEEFSG
101-150101RGEQATFDWL111FKGYGIAFSS121GERAKQLRRF131SITTLRDFGV141GKRGIEERIQ
151-200151EEAGFLIDSF161RKTNGAFIDP171TFYLSRTVSN181VISSIVFGDR191FDYEDKEFLS
201-250201LLRMMLGSLQ211FTATSMGQVY221EMFSSVMKHL231PGPQQQAFKE241LQGLEDFITK
251-300251KVEHNQRTLD261PNSPRDFIDS271FLIRMLEEKK281NPNTEFYMKN291LVLTTLNLFF
301-350301AGTETVSTTL311RYGFLLLMKY321PDIEAKVHEE331IDRVIGRNRQ341PKYEDRMKMP
351-400351YTEAVIHEIQ361RFADLIPMGL371ARRVTKDTKF381RDFLLPKGTE391VFPMLGSVLK
401-450401DPKFFSNPKD411FNPKHFLDDK421GQFKKSDAFV431PFSIGKRYCF441GEGLARMELF
451-494451LFLTNIMQNF461HFKSTQEPQD471IDVSPRLVGF481VTIPPTYTMS491FLSR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
82 SWISSPALM DBPTM CYSMODDB Cytochrome P450
Liver (28526873)
-
GPS-Palm: 0.93
Deep-Palm: 0.98
439 SWISSPALM DBPTM CYSMODDB Cytochrome P450
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Liver
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine