Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P15880 | RPS2 | Small ribosomal subunit protein uS5 … | Homo sapiens (Human) | 293 aa |
Protein Details: P15880 (RPS2)
Protein Information
| Accession | P15880 |
|---|---|
| Protein Names | Small ribosomal subunit protein uS5 (40S ribosomal protein S2) (40S ribosomal protein S4) (Protein LLRep3) |
| Gene Symbol | RPS2 |
| Organism | Homo sapiens (Human) |
| Length | 293 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MADDAGAAGG11PGGPGGPGMG21NRGGFRGGFG31SGIRGRGRGR41GRGRGRGRGA
51-10051RGGKAEDKEW61MPVTKLGRLV71KDMKIKSLEE81IYLFSLPIKE91SEIIDFFLGA
101-150101SLKDEVLKIM111PVQKQTRAGQ121RTRFKAFVAI131GDYNGHVGLG141VKCSKEVATA
151-200151IRGAIILAKL161SIVPVRRGYW171GNKIGKPHTV181PCKVTGRCGS191VLVRLIPAPR
201-250201GTGIVSAPVP211KKLLMMAGID221DCYTSARGCT231ATLGNFAKAT241FDAISKTYSY
251-293251LTPDLWKETV261FTKSPYQEFT271DHLVKTHTRV281SVQRTQAPAV291ATT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 143 | - | - | - |
Deep-Palm: 0.96
|
|
| 182 | - |
SW480 cell line
(26865113)
| - |
Deep-Palm: 0.95
|
|
| 188 | - | - | - |
Deep-Palm: 0.97
|
|
| 222 | - | - | - |
Deep-Palm: 0.94
|
|
| 229 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein S5 C-terminal domain |
SW480 cell line
(26865113)
|
cerebral cortex
(36430497)
|
Deep-Palm: 0.76
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
3
LNCaP
Specificity: 0.250
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.250
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.167
2/2 (100.0%)
1
293T cell
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Cerebral Cortex (Mass)
Specificity: 0.250
3/4 (75.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 119 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 187 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 194 | R → C | 0.007299 | SNP | Missense Mutation | READ |