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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P15880 RPS2; RPS4 Small ribosomal subunit protein uS5 … Homo sapiens (Human) 293 aa

Protein Details: P15880 (RPS2)

Protein Information
Accession P15880
Protein Names Small ribosomal subunit protein uS5 (40S ribosomal protein S2) (40S ribosomal protein S4) (Protein LLRep3)
Gene Symbol RPS2; RPS4
Organism Homo sapiens (Human)
Length 293 aa
Isoforms No isoforms
Related PMIDs 19137006 19801377 21076176 29733200 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.569
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.569
33/46 (71.7%)
10
HAP1 cells
Specificity: 0.172
10/10 (100.0%)
8
Jurkat T cells
Specificity: 0.138
8/25 (32.0%)
4
293T cells
Specificity: 0.069
4/10 (40.0%)
3
PC3 cells
Specificity: 0.052
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADDAGAAGG11PGGPGGPGMG21NRGGFRGGFG31SGIRGRGRGR41GRGRGRGRGA
51-10051RGGKAEDKEW61MPVTKLGRLV71KDMKIKSLEE81IYLFSLPIKE91SEIIDFFLGA
101-150101SLKDEVLKIM111PVQKQTRAGQ121RTRFKAFVAI131GDYNGHVGLG141VKCSKEVATA
151-200151IRGAIILAKL161SIVPVRRGYW171GNKIGKPHTV181PCKVTGRCGS191VLVRLIPAPR
201-250201GTGIVSAPVP211KKLLMMAGID221DCYTSARGCT231ATLGNFAKAT241FDAISKTYSY
251-293251LTPDLWKETV261FTKSPYQEFT271DHLVKTHTRV281SVQRTQAPAV291ATT
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
143 Prediction (Low) - -
182 Prediction (Medium) - -
188 Prediction (Low) - -
222 Experimental Prediction (High) Ribosomal protein S5 C-terminal domain 19801377
229 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Ribosomal protein S5 C-terminal domain -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
119 G → C 0.001764 SNP Missense Mutation LUAD
187 R → C 0.003774 SNP Missense Mutation UCEC
194 R → C 0.007299 SNP Missense Mutation READ