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UniProt ID Gene Symbol Protein Name Organism Length Action
P16671 CD36 Platelet glycoprotein 4 (Fatty acid … Homo sapiens (Human) 472 aa

Protein Details: P16671 (CD36)

Protein Information
AccessionP16671
Protein NamesPlatelet glycoprotein 4 (Fatty acid translocase) (FAT) (Glycoprotein IIIb) (GPIIIB) (Leukocyte differentiation antigen CD36) (PAS IV) (PAS-4) (Platelet collagen receptor) (Platelet glycoprotein IV) (GPIV) (Thrombospondin receptor) (CD antigen CD36)
Gene SymbolCD36
OrganismHomo sapiens (Human)
Length472 aa
IsoformsNo isoforms
Related PMIDs 26111759 33636221
Database SourcesPTMDdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCDRNCGLI11AGAVIGAVLA21VFGGILMPVG31DLLIQKTIKK41QVVLEEGTIA
51-10051FKNWVKTGTE61VYRQFWIFDV71QNPQEVMMNS81SNIQVKQRGP91YTYRVRFLAK
101-150101ENVTQDAEDN111TVSFLQPNGA121IFEPSLSVGT131EADNFTVLNL141AVAAASHIYQ
151-200151NQFVQMILNS161LINKSKSSMF171QVRTLRELLW181GYRDPFLSLV191PYPVTTTVGL
201-250201FYPYNNTADG211VYKVFNGKDN221ISKVAIIDTY231KGKRNLSYWE241SHCDMINGTD
251-300251AASFPPFVEK261SQVLQFFSSD271ICRSIYAVFE281SDVNLKGIPV291YRFVLPSKAF
301-350301ASPVENPDNY311CFCTEKIISK321NCTSYGVLDI331SKCKEGRPVY341ISLPHFLYAS
351-400351PDVSEPIDGL361NPNEEEHRTY371LDIEPITGFT381LQFAKRLQVN391LLVKPSEKIQ
401-450401VLKNLKRNYI411VPILWLNETG421TIGDEKANMF431RSQVTGKINL441LGLIEMILLS
451-472451VGVVMFVAFM461ISYCACRSKT471IK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
3 DBPTM SWISSPALM CD36/scavenger receptor class B member 1 - -
GPS-Palm: 0.96
Deep-Palm: 0.02
7 DBPTM SWISSPALM CD36/scavenger receptor class B member 1 - -
GPS-Palm: 0.95
Deep-Palm: 0.04
243 - - -
Deep-Palm: 0.09
272 - - -
GPS-Palm: 0.72
Deep-Palm: 0.74
311 - - -
Deep-Palm: 0.11
313 - - -
Deep-Palm: 0.12
322 - - -
GPS-Palm: 0.68
Deep-Palm: 0.08
333 - - -
Deep-Palm: 0.62
464 DBPTM SWISSPALM - - -
GPS-Palm: 0.95
Deep-Palm: 0.02
466 DBPTM SWISSPALM - - -
GPS-Palm: 0.96
Deep-Palm: 0.02
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Primary T cell
Specificity: 0.800
4/4 (100.0%)
1
heart
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
96 R → C 0.001887 SNP Missense Mutation UCEC
186 F → C 0.002033 SNP Missense Mutation LUSC
192 Y → C 0.001887 SNP Missense Mutation UCEC
276 Y → C 0.002294 SNP Missense Mutation OV
293 F → C 0.001887 SNP Missense Mutation UCEC
340 Y → C 0.002427 SNP Missense Mutation BLCA