Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P17081 | RHOQ | Rho-related GTP-binding protein RhoQ (Ras-like … | Homo sapiens (Human) | 205 aa |
Protein Details: P17081 (RHOQ)
Protein Information
| Accession | P17081 |
|---|---|
| Protein Names | Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A) |
| Gene Symbol | RHOQ |
| Organism | Homo sapiens (Human) |
| Length | 205 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAHGPGALML11KCVVVGDGAV21GKTCLLMSYA31NDAFPEEYVP41TVFDHYAVSV
51-10051TVGGKQYLLG61LYDTAGQEDY71DRLRPLSYPM81TDVFLICFSV91VNPASFQNVK
101-150101EEWVPELKEY111APNVPFLLIG121TQIDLRDDPK131TLARLNDMKE141KPICVEQGQK
151-200151LAKEIGACCY161VECSALTQKG171LKTVFDEAII181AILTPKKHTV191KKRIGSRCIN
201-205201CCLIT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 12 | SWISSPALM DBPTM CYSMODDB | Ras family P-loop containing nucleoside triphosphate hydrolase Small GTPase | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.75
Deep-Palm: 0.93
|
| 24 | Transforming protein P21 ras signature P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase Rho | - | - |
Deep-Palm: 0.93
|
|
| 87 | - | - | - |
Deep-Palm: 0.86
|
|
| 144 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 158 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.98
|
|
| 159 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.83
Deep-Palm: 0.98
|
|
| 163 | SWISSPALM DBPTM CYSMODDB | Ras family | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.71
Deep-Palm: 0.98
|
| 198 | SWISSPALM | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.02
|
| 201 | SWISSPALM | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.02
|
| 202 | - | - | - |
GPS-Palm: 0.98
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
1
heart
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
LNCaP cells (Mass)
Specificity: 0.200
1/4 (25.0%)
1
Cerebral Cortex (Mass)
Specificity: 0.200
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 159 | C → C | 0.002506 | SNP | Silent | COAD |
| ? | ? → ? | 0.002033 | SNP | Missense Mutation | LUSC |