Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P17182 Eno1 Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) … Mus musculus (Mouse) 434 aa

Protein Details: P17182 (Eno1)

Protein Information
AccessionP17182
Protein NamesAlpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 1) (Non-neural enolase) (NNE)
Gene SymbolEno1
OrganismMus musculus (Mouse)
Length434 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSILRIHARE11IFDSRGNPTV21EVDLYTAKGL31FRAAVPSGAS41TGIYEALELR
51-10051DNDKTRFMGK61GVSQAVEHIN71KTIAPALVSK81KVNVVEQEKI91DKLMIEMDGT
101-150101ENKSKFGANA111ILGVSLAVCK121AGAVEKGVPL131YRHIADLAGN141PEVILPVPAF
151-200151NVINGGSHAG161NKLAMQEFMI171LPVGASSFRE181AMRIGAEVYH191NLKNVIKEKY
201-250201GKDATNVGDE211GGFAPNILEN221KEALELLKTA231IAKAGYTDQV241VIGMDVAASE
251-300251FYRSGKYDLD261FKSPDDPSRY271ITPDQLADLY281KSFVQNYPVV291SIEDPFDQDD
301-350301WGAWQKFTAS311AGIQVVGDDL321TVTNPKRIAK331AASEKSCNCL341LLKVNQIGSV
351-400351TESLQACKLA361QSNGWGVMVS371HRSGETEDTF381IADLVVGLCT391GQIKTGAPCR
401-434401SERLAKYNQI411LRIEEELGSK421AKFAGRSFRN431PLAK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
119 - -
Brain (35358180)
GPS-Palm: 0.89
Deep-Palm: 0.98
337 Enolase, C-terminal TIM barrel domain
Brain (34200797)
brain (39008777)
MLE (39008777)
Brain (35358180)
GPS-Palm: 0.92
Deep-Palm: 0.98
339 Enolase, C-terminal TIM barrel domain
Brain (34200797)
brain (39008777)
MLE (39008777)
Brain (35358180)
GPS-Palm: 0.85
Deep-Palm: 0.97
357 SWISSPALM DBPTM CYSMODDB Enolase C-terminal TIM barrel domain
Liver (28526873)
-
GPS-Palm: 0.82
Deep-Palm: 0.92
389 SWISSPALM DBPTM CYSMODDB Enolase C-terminal TIM barrel domain
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.90
Deep-Palm: 0.97
399 - - -
GPS-Palm: 0.89
Deep-Palm: 0.95
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
5
Liver
Specificity: 0.104
5/5 (100.0%)
5
Brain
Specificity: 0.104
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.763
29
Brain tissue (Mass)
Specificity: 0.604
29/56 (51.8%)
9
Macrophage Raw 264.7 (Mass)
Specificity: 0.188
9/10 (90.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine