Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P17427 Ap2a2; Adtab AP-2 complex subunit alpha-2 (100 … Mus musculus (Mouse) 938 aa

Protein Details: P17427 (Ap2a2)

Protein Information
Accession P17427
Protein Names AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene Symbol Ap2a2; Adtab
Organism Mus musculus (Mouse)
Length 938 aa
Isoforms No isoforms
Related PMIDs 26165157 28526873 28680068 29733200 31311849 31772009 34200797 35358180 37925639
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.576
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.576
19/19 (100.0%)
11
Brain tissue
Specificity: 0.333
11/12 (91.7%)
3
Neural Stem Cells
Specificity: 0.091
3/3 (100.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Testis
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPAVSKGDGM11RGLAVFISDI21RNCKSKEAEI31KRINKELANI41RSKFKGDKAL
51-10051DGYSKKKYVC61KLLFIFLLGH71DIDFGHMEAV81NLLSSNRYTE91KQIGYLFISV
101-150101LVNSNSELIR111LINNAIKNDL121ASRNPTFMGL131ALHCIANVGS141REMAEAFAGE
151-200151IPKILVAGDT161MDSVKQSAAL171CLLRLYRTSP181DLVPMGDWTS191RVVHLLNDQH
201-250201LGVVTAATSL211ITTLAQKNPE221EFKTSVSLAV231SRLSRIVTSA241STDLQDYTYY
251-300251FVPAPWLSVK261LLRLLQCYPP271PDPAVRGRLT281ECLETILNKA291QEPPKSKKVQ
301-350301HSNAKNAVLF311EAISLIIHHD321SEPNLLVRAC331NQLGQFLQHR341ETNLRYLALE
351-400351SMCTLASSEF361SHEAVKTHIE371TVINALKTER381DVSVRQRAVD391LLYAMCDRSN
401-450401AQQIVAEMLS411YLETADYSIR421EEIVLKVAIL431AEKYAVDYTW441YVDTILNLIR
451-500451IAGDYVSEEV461WYRVIQIVIN471RDDVQGYAAK481TVFEALQAPA491CHENLVKVGG
501-550501YILGEFGNLI511AGDPRSSPLI521QFNLLHSKFH531LCSVPTRALL541LSTYIKFVNL
551-600551FPEVKATIQD561VLRSDSQLKN571ADVELQQRAV581EYLRLSTVAS591TDILATVLEE
601-650601MPPFPERESS611ILAKLKKKKG621PSTVTDLEET631KRERSIDVNG641GPEPVPASTS
651-700651AASTPSPSAD661LLGLGAVPPA671PTGPPPSSGG681GLLVDVFSDS691ASAVAPLAPG
701-750701SEDNFARFVC711KNNGVLFENQ721LLQIGLKSEF731RQNLGRMFIF741YGNKTSTQFL
751-800751NFTPTLICAD761DLQTNLNLQT771KPVDPTVDGG781AQVQQVVNIE791CISDFTEAPV
801-850801LNIQFRYGGT811FQNVSVKLPI821TLNKFFQPTE831MASQDFFQRW841KQLSNPQQEV
851-900851QNIFKAKHPM861DTEITKAKII871GFGSALLEEV881DPNPANFVGA891GIIHTKTTQI
901-938901GCLLRLEPNL911QAQMYRLTLR921TSKDTVSQRL931CELLSEQF
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
23 Prediction (Medium) - -
60 Prediction (Low) - -
134 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Adaptin N terminal region 28680068
171 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Adaptin N terminal region 31311849, 28526873
267 Prediction (Medium) - -
282 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) - 28526873
330 Experimental CYSMODDB Prediction (Medium) Adaptin N terminal region 26165157, 31311849, 34200797, 28526873
353 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Adaptin N terminal region 28526873
396 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Adaptin N terminal region 28526873
491 Experimental Adaptin N terminal region 34200797
532 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) - 28526873
902 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Alpha adaptin AP2 C-terminal domain 31311849, 28526873
931 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons