Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P17516 | AKR1C4; CHDR | Aldo-keto reductase family 1 member … | Homo sapiens (Human) | 323 aa |
Protein Details: P17516 (AKR1C4)
Protein Information
| Accession | P17516 |
|---|---|
| Protein Names | Aldo-keto reductase family 1 member C4 (EC 1.1.1.-) (EC 1.1.1.209) (EC 1.1.1.210) (EC 1.1.1.51) (EC 1.1.1.53) (EC 1.1.1.62) (3-alpha-hydroxysteroid dehydrogenase type I) (3-alpha-HSD1) (EC 1.1.1.357) (3alpha-hydroxysteroid 3-dehydrogenase) (Chlordecone reductase) (CDR) (EC 1.1.1.225) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4) (HAKRA) |
| Gene Symbol | AKR1C4; CHDR |
| Organism | Homo sapiens (Human) |
| Length | 323 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDPKYQRVEL11NDGHFMPVLG21FGTYAPPEVP31RNRAVEVTKL41AIEAGFRHID
51-10051SAYLYNNEEQ61VGLAIRSKIA71DGSVKREDIF81YTSKLWCTFF91QPQMVQPALE
101-150101SSLKKLQLDY111VDLYLLHFPM121ALKPGETPLP131KDENGKVIFD141TVDLSATWEV
151-200151MEKCKDAGLA161KSIGVSNFNC171RQLEMILNKP181GLKYKPVCNQ191VECHPYLNQS
201-250201KLLDFCKSKD211IVLVAHSALG221TQRHKLWVDP231NSPVLLEDPV241LCALAKKHKQ
251-300251TPALIALRYQ261LQRGVVVLAK271SYNEQRIREN281IQVFEFQLTS291EDMKVLDGLN
301-323301RNYRYVVMDF311LMDHPDYPFS321DEY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 170 | Prediction (Medium) | - | - |
| 206 | CYSMODDB SWISSPALM DBPTM | Aldo/keto reductase family | - |
| 242 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 47 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 258 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 258 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 323 | Y → C | 0.003774 | SNP | Missense Mutation | UCEC |