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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P17661 DES Desmin Homo sapiens (Human) 470 aa

Protein Details: P17661 (DES)

Protein Information
Accession P17661
Protein Names Desmin
Gene Symbol DES
Organism Homo sapiens (Human)
Length 470 aa
Isoforms No isoforms
Related PMIDs 24357059
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Endothelial cells
Specificity: 1.000
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSQAYSSSQR11VSSYRRTFGG21APGFPLGSPL31SSPVFPRAGF41GSKGSSSSVT
51-10051SRVYQVSRTS61GGAGGLGSLR71ASRLGTTRTP81SSYGAGELLD91FSLADAVNQE
101-150101FLTTRTNEKV111ELQELNDRFA121NYIEKVRFLE131QQNAALAAEV141NRLKGREPTR
151-200151VAELYEEELR161ELRRQVEVLT171NQRARVDVER181DNLLDDLQRL191KAKLQEEIQL
201-250201KEEAENNLAA211FRADVDAATL221ARIDLERRIE231SLNEEIAFLK241KVHEEEIREL
251-300251QAQLQEQQVQ261VEMDMSKPDL271TAALRDIRAQ281YETIAAKNIS291EAEEWYKSKV
301-350301SDLTQAANKN311NDALRQAKQE321MMEYRHQIQS331YTCEIDALKG341TNDSLMRQMR
351-400351ELEDRFASEA361SGYQDNIARL371EEEIRHLKDE381MARHLREYQD391LLNVKMALDV
401-450401EIATYRKLLE411GEESRINLPI421QTYSALNFRE431TSPEQRGSEV441HTKKTVMIKT
451-470451IETRDGEVVS461EATQQQHEVL
Palmitoylation Sites Details

No known palmitoylation sites

Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
222 R → C 0.002506 SNP Missense Mutation COAD
315 R → C 0.007299 SNP Missense Mutation READ
369 R → C 0.001887 SNP Missense Mutation UCEC
386 R → C 0.002545 SNP Missense Mutation GBM