Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P17742 | Ppia | Peptidyl-prolyl cis-trans isomerase A (PPIase … | Mus musculus (Mouse) | 164 aa |
Protein Details: P17742 (Ppia)
Protein Information
| Accession | P17742 |
|---|---|
| Protein Names | Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) (SP18) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed] |
| Gene Symbol | Ppia |
| Organism | Mus musculus (Mouse) |
| Length | 164 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVNPTVFFDI11TADDEPLGRV21SFELFADKVP31KTAENFRALS41TGEKGFGYKG
51-10051SSFHRIIPGF61MCQGGDFTRH71NGTGGRSIYG81EKFEDENFIL91KHTGPGILSM
101-150101ANAGPNTNGS111QFFICTAKTE121WLDGKHVVFG131KVKEGMNIVE141AMERFGSRNG
151-164151KTSKKITISD161CGQL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 62 | SWISSPALM DBPTM CYSMODDB | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD |
Liver
(28526873)
brain
(39008777)
|
Brain
(35358180)
|
GPS-Palm: 0.84
Deep-Palm: 0.52
|
| 115 | SWISSPALM DBPTM CYSMODDB | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD |
Brain
(31311849)
Liver
(28526873)
|
Brain
(35358180)
Macrophage Raw 264.7
(29217618)
Brain
(31311849)
|
GPS-Palm: 0.88
Deep-Palm: 0.24
|
| 161 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.97
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
6
Liver
Specificity: 0.092
6/6 (100.0%)
6
Brain
Specificity: 0.092
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.849
45
Brain tissue (Mass)
Specificity: 0.692
45/56 (80.4%)
8
Macrophage Raw 264.7 (Mass)
Specificity: 0.123
8/10 (80.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.