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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P17980 PSMC3; TBP1 26S proteasome regulatory subunit 6A … Homo sapiens (Human) 439 aa

Protein Details: P17980 (PSMC3)

Protein Information
Accession P17980
Protein Names 26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene Symbol PSMC3; TBP1
Organism Homo sapiens (Human)
Length 439 aa
Isoforms No isoforms
Related PMIDs 19137006 29733200 31251020 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.385
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
10
HAP1 cells
Specificity: 0.385
10/10 (100.0%)
6
LNCaP cells
Specificity: 0.231
6/46 (13.0%)
4
293T cells
Specificity: 0.154
4/10 (40.0%)
3
Jurkat T cells
Specificity: 0.115
3/25 (12.0%)
3
PC3 cells
Specificity: 0.115
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNLLPNIESP11VTRQEKMATV21WDEAEQDGIG31EEVLKMSTEE41IIQRTRLLDS
51-10051EIKIMKSEVL61RVTHELQAMK71DKIKENSEKI81KVNKTLPYLV91SNVIELLDVD
101-150101PNDQEEDGAN111IDLDSQRKGK121CAVIKTSTRQ131TYFLPVIGLV141DAEKLKPGDL
151-200151VGVNKDSYLI161LETLPTEYDS171RVKAMEVDER181PTEQYSDIGG191LDKQIQELVE
201-250201AIVLPMNHKE211KFENLGIQPP221KGVLMYGPPG231TGKTLLARAC241AAQTKATFLK
251-300251LAGPQLVQMF261IGDGAKLVRD271AFALAKEKAP281SIIFIDELDA291IGTKRFDSEK
301-350301AGDREVQRTM311LELLNQLDGF321QPNTQVKVIA331ATNRVDILDP341ALLRSGRLDR
351-400351KIEFPMPNEE361ARARIMQIHS371RKMNVSPDVN381YEELARCTDD391FNGAQCKAVC
401-439401VEAGMIALRR411GATELTHEDY421MEGILEVQAK431KKANLQYYA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
121 Prediction (Medium) - -
240 Prediction (High) - -
400 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
132 Y → C 0.001887 SNP Missense Mutation UCEC
264 G → C 0.002288 SNP Missense Mutation STAD
264 G → C 0.005435 SNP Missense Mutation ESCA
396 C → Y 0.001887 SNP Missense Mutation UCEC