Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P18085 | ARF4 | ADP-ribosylation factor 4 | Homo sapiens (Human) | 180 aa |
Protein Details: P18085 (ARF4)
Protein Information
| Accession | P18085 |
|---|---|
| Protein Names | ADP-ribosylation factor 4 |
| Gene Symbol | ARF4 |
| Organism | Homo sapiens (Human) |
| Length | 180 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 29733200 31251020 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLTISSLFS11RLFGKKQMRI21LMVGLDAAGK31TTILYKLKLG41EIVTTIPTIG
51-10051FNVETVEYKN61ICFTVWDVGG71QDRIRPLWKH81YFQNTQGLIF91VVDSNDRERI
101-150101QEVADELQKM111LLVDELRDAV121LLLFANKQDL131PNAMAISEMT141DKLGLQSLRN
151-180151RTWYVQATCA161TQGTGLYEGL171DWLSNELSKR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 62 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.72
Deep-Palm: 0.88
|
|
| 159 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.85
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
2
LNCaP
Specificity: 0.286
2/2 (100.0%)
2
HAP1 cell
Specificity: 0.286
2/2 (100.0%)
2
293T cell
Specificity: 0.286
2/2 (100.0%)
1
EC cell
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 149 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 149 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |