Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P18440 | NAT1 | Arylamine N-acetyltransferase 1 (EC 2.3.1.5) … | Homo sapiens (Human) | 290 aa |
Protein Details: P18440 (NAT1)
Protein Information
| Accession | P18440 |
|---|---|
| Protein Names | Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Monomorphic arylamine N-acetyltransferase) (MNAT) (N-acetyltransferase type 1) (NAT-1) |
| Gene Symbol | NAT1 |
| Organism | Homo sapiens (Human) |
| Length | 290 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDIEAYLERI11GYKKSRNKLD21LETLTDILQH31QIRAVPFENL41NIHCGDAMDL
51-10051GLEAIFDQVV61RRNRGGWCLQ71VNHLLYWALT81TIGFETTMLG91GYVYSTPAKK
101-150101YSTGMIHLLL111QVTIDGRNYI121VDAGFGRSYQ131MWQPLELISG141KDQPQVPCVF
151-200151RLTEENGFWY161LDQIRREQYI171PNEEFLHSDL181LEDSKYRKIY191SFTLKPRTIE
201-250201DFESMNTYLQ211TSPSSVFTSK221SFCSLQTPDG231VHCLVGFTLT241HRRFNYKDNT
251-290251DLIEFKTLSE261EEIEKVLKNI271FNISLQRKLV281PKHGDRFFTI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 44 | Arylamine N-acetyltransferase Papain-like cysteine peptidase superfamily | - | - |
Deep-Palm: 0.42
|
|
| 68 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.80
|
|
| 148 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.85
|
|
| 223 | - | - | - |
Deep-Palm: 0.69
|
|
| 233 | - | - | - |
Deep-Palm: 0.52
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Primary T cell
Specificity: 0.800
4/4 (100.0%)
1
LNCaP
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 12 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 191 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 192 | F → C | 0.002288 | SNP | Missense Mutation | STAD |
| 231 | V → Cfs*2 | 0.001887 | INS | Nonsense Mutation | UCEC |