Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P18760 | Cfl1 | Cofilin-1 (Cofilin, non-muscle isoform) | Mus musculus (Mouse) | 166 aa |
Protein Details: P18760 (Cfl1)
Protein Information
| Accession | P18760 |
|---|---|
| Protein Names | Cofilin-1 (Cofilin, non-muscle isoform) |
| Gene Symbol | Cfl1 |
| Organism | Mus musculus (Mouse) |
| Length | 166 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASGVAVSDG11VIKVFNDMKV21RKSSTPEEVK31KRKKAVLFCL41SEDKKNIILE
51-10051EGKEILVGDV61GQTVDDPYTT71FVKMLPDKDC81RYALYDATYE91TKESKKEDLV
101-150101FIFWAPENAP111LKSKMIYASS121KDAIKKKLTG131IKHELQANCY141EEVKDRCTLA
151-166151EKLGGSAVIS161LEGKPL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | SWISSPALM DBPTM CYSMODDB | Actin depolymerizing proteins ADF-H/Gelsolin-like domain superfamily |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.95
Deep-Palm: 0.98
|
| 80 | Cofilin/tropomyosin-type actin-binding protein |
Brain
(34200797)
| - |
Deep-Palm: 0.60
|
|
| 139 | Cofilin/tropomyosin-type actin-binding protein |
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.92
|
|
| 147 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Brain
Specificity: 0.136
6/6 (100.0%)
5
Liver
Specificity: 0.114
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
33
Brain tissue (Mass)
Specificity: 0.750
33/56 (58.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.