Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P20444 Prkca; Pkca Protein kinase C alpha type … Mus musculus (Mouse) 672 aa

Protein Details: P20444 (Prkca)

Protein Information
Accession P20444
Protein Names Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene Symbol Prkca; Pkca
Organism Mus musculus (Mouse)
Length 672 aa
Isoforms No isoforms
Related PMIDs 28680068 29733200 34200797 35358180 37925639
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
12
Liver tissue
Specificity: 0.667
12/19 (63.2%)
6
Brain tissue
Specificity: 0.333
6/12 (50.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
0
Testis
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADVYPANDS11TASQDVANRF21ARKGALRQKN31VHEVKDHKFI41ARFFKQPTFC
51-10051SHCTDFIWGF61GKQGFQCQVC71CFVVHKRCHE81FVTFSCPGAD91KGPDTDDPRS
101-150101KHKFKIHTYG111SPTFCDHCGS121LLYGLIHQGM131KCDTCDMNVH141KQCVINDPSL
151-200151CGMDHTEKRG161RIYLKAEVTD171EKLHVTVRDA181KNLIPMDPNG191LSDPYVKLKL
201-250201IPDPKNESKQ211KTKTIRSNLN221PQWNESFTFK231LKPSDKDRRL241SVEIWDWDRT
251-300251TRNDFMGSLS261FGVSELMKMP271ASGWYKAHNQ281EEGEYYNVPI291PEGDEEGNME
301-350301LRQKFEKAKL311GPVGNKVISP321SEDRKQPSNN331LDRVKLTDFN341FLMVLGKGSF
351-400351GKVMLADRKG361TEELYAIKIL371KKDVVIQDDD381VECTMVEKRV391LALLDKPPFL
401-450401TQLHSCFQTV411DRLYFVMEYV421NGGDLMYHIQ431QVGKFKEPQA441VFYAAEISIG
451-500451LFFLHKRGII461YRDLKLNNVM471LNSEGHIKIA481DFGMCKEHMM491DGVTTRTFCG
501-550501TPDYIAPEII511AYQPYGKSVD521WWAYGVLLYE531MLAGQPPFDG541EDEDELFQSI
551-600551MEHNVSYPKS561LSKEAVSICK571GLMTKQPAKR581LGCGPEGERD591VREHAFFRRI
601-650601DWEKLENREI611QPPFKPKVCG621KGAENFDKFF631TRGQPVLTPP641DQLVIANIDQ
651-672651SDFEGFSYVN661PQFVHPILQS671AV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
50 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Phorbol esters/diacylglycerol binding domain (C1 domain) 28680068
53 Experimental Phorbol esters/diacylglycerol binding domain (C1 domain) 28680068
67 Prediction (Medium) - -
70 Prediction (Low) - -
71 Prediction (Low) - -
86 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) Phorbol esters/diacylglycerol binding domain (C1 domain) 28680068
406 Prediction (Low) - -
485 Experimental Protein kinase domain 35358180
499 Experimental Protein kinase domain 34200797
569 Prediction (High) - -
583 Experimental Prediction (Medium) - 34200797
619 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons