Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P20444 | Prkca | Protein kinase C alpha type … | Mus musculus (Mouse) | 672 aa |
Protein Details: P20444 (Prkca)
Protein Information
| Accession | P20444 |
|---|---|
| Protein Names | Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13) |
| Gene Symbol | Prkca |
| Organism | Mus musculus (Mouse) |
| Length | 672 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 34200797 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MADVYPANDS11TASQDVANRF21ARKGALRQKN31VHEVKDHKFI41ARFFKQPTFC
51-10051SHCTDFIWGF61GKQGFQCQVC71CFVVHKRCHE81FVTFSCPGAD91KGPDTDDPRS
101-150101KHKFKIHTYG111SPTFCDHCGS121LLYGLIHQGM131KCDTCDMNVH141KQCVINDPSL
151-200151CGMDHTEKRG161RIYLKAEVTD171EKLHVTVRDA181KNLIPMDPNG191LSDPYVKLKL
201-250201IPDPKNESKQ211KTKTIRSNLN221PQWNESFTFK231LKPSDKDRRL241SVEIWDWDRT
251-300251TRNDFMGSLS261FGVSELMKMP271ASGWYKAHNQ281EEGEYYNVPI291PEGDEEGNME
301-350301LRQKFEKAKL311GPVGNKVISP321SEDRKQPSNN331LDRVKLTDFN341FLMVLGKGSF
351-400351GKVMLADRKG361TEELYAIKIL371KKDVVIQDDD381VECTMVEKRV391LALLDKPPFL
401-450401TQLHSCFQTV411DRLYFVMEYV421NGGDLMYHIQ431QVGKFKEPQA441VFYAAEISIG
451-500451LFFLHKRGII461YRDLKLNNVM471LNSEGHIKIA481DFGMCKEHMM491DGVTTRTFCG
501-550501TPDYIAPEII511AYQPYGKSVD521WWAYGVLLYE531MLAGQPPFDG541EDEDELFQSI
551-600551MEHNVSYPKS561LSKEAVSICK571GLMTKQPAKR581LGCGPEGERD591VREHAFFRRI
601-650601DWEKLENREI611QPPFKPKVCG621KGAENFDKFF631TRGQPVLTPP641DQLVIANIDQ
651-672651SDFEGFSYVN661PQFVHPILQS671AV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 50 | SWISSPALM DBPTM CYSMODDB | PROTEIN KINASE C, MU Phorbol esters/diacylglycerol binding domain (C1 domain) Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Diacylglycerol/phorbol-ester binding C1-like domain superfamily |
Forebrain
(28680068)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.87
Deep-Palm: 0.04
|
| 53 | - | - |
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.03
|
|
| 67 | - | - |
Brain
(31311849)
|
GPS-Palm: 0.86
Deep-Palm: 0.02
|
|
| 70 | - | - |
Brain
(31311849)
|
GPS-Palm: 0.68
Deep-Palm: 0.02
|
|
| 71 | - | - |
Brain
(31311849)
|
GPS-Palm: 0.77
Deep-Palm: 0.02
|
|
| 78 | - | - |
Brain
(31311849)
|
Deep-Palm: 0.04
|
|
| 86 | SWISSPALM DBPTM CYSMODDB | Phorbol esters/diacylglycerol binding domain (C1 domain) |
Forebrain
(28680068)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.65
Deep-Palm: 0.17
|
| 115 | - | - | - |
Deep-Palm: 0.05
|
|
| 118 | - | - | - |
Deep-Palm: 0.04
|
|
| 132 | - | - | - |
Deep-Palm: 0.03
|
|
| 135 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.02
|
|
| 143 | - | - | - |
Deep-Palm: 0.02
|
|
| 151 | - | - | - |
Deep-Palm: 0.16
|
|
| 383 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.95
|
|
| 406 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.67
Deep-Palm: 0.55
|
|
| 485 | - | - | - |
Deep-Palm: 0.06
|
|
| 499 | Protein kinase domain |
Brain
(34200797)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.10
|
|
| 569 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.94
|
|
| 583 | - |
Brain
(34200797)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.83
Deep-Palm: 0.84
|
|
| 619 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.92
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
Brain
Specificity: 0.300
3/3 (100.0%)
2
Liver
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Brain tissue (Mass)
Specificity: 0.500
5/56 (8.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.