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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P20591 MX1 Interferon-induced GTP-binding protein Mx1 (Interferon-induced … Homo sapiens (Human) 662 aa

Protein Details: P20591 (MX1)

Protein Information
AccessionP20591
Protein NamesInterferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1) [Cleaved into: Interferon-induced GTP-binding protein Mx1, N-terminally processed]
Gene SymbolMX1
OrganismHomo sapiens (Human)
Length662 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVVSEVDIAK11ADPAAASHPL21LLNGDATVAQ31KNPGSVAENN41LCSQYEEKVR
51-10051PCIDLIDSLR61ALGVEQDLAL71PAIAVIGDQS81SGKSSVLEAL91SGVALPRGSG
101-150101IVTRCPLVLK111LKKLVNEDKW121RGKVSYQDYE131IEISDASEVE141KEINKAQNAI
151-200151AGEGMGISHE161LITLEISSRD171VPDLTLIDLP181GITRVAVGNQ191PADIGYKIKT
201-250201LIKKYIQRQE211TISLVVVPSN221VDIATTEALS231MAQEVDPEGD241RTIGILTKPD
251-300251LVDKGTEDKV261VDVVRNLVFH271LKKGYMIVKC281RGQQEIQDQL291SLSEALQREK
301-350301IFFENHPYFR311DLLEEGKATV321PCLAEKLTSE331LITHICKSLP341LLENQIKETH
351-400351QRITEELQKY361GVDIPEDENE371KMFFLIDKVN381AFNQDITALM391QGEETVGEED
401-450401IRLFTRLRHE411FHKWSTIIEN421NFQEGHKILS431RKIQKFENQY441RGRELPGFVN
451-500451YRTFETIVKQ461QIKALEEPAV471DMLHTVTDMV481RLAFTDVSIK491NFEEFFNLHR
501-550501TAKSKIEDIR511AEQEREGEKL521IRLHFQMEQI531VYCQDQVYRG541ALQKVREKEL
551-600551EEEKKKKSWD561FGAFQSSSAT571DSSMEEIFQH581LMAYHQEASK591RISSHIPLII
601-650601QFFMLQTYGQ611QLQKAMLQLL621QDKDTYSWLL631KERSDTSDKR641KFLKERLARL
651-662651TQARRRLAQF661PG
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
42 - - -
Deep-Palm: 0.86
52 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.84
Deep-Palm: 0.98
105 - - -
GPS-Palm: 0.85
Deep-Palm: 0.98
280 - - -
GPS-Palm: 0.86
Deep-Palm: 0.71
322 - - -
GPS-Palm: 0.88
Deep-Palm: 0.98
336 - - -
GPS-Palm: 0.69
Deep-Palm: 0.96
533 - - -
Deep-Palm: 0.86
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
105 C → Y 0.002294 SNP Missense Mutation OV
205 Y → C 0.002506 SNP Missense Mutation COAD
280 C → S 0.001887 SNP Missense Mutation UCEC
322 C → C 0.001887 SNP Silent UCEC
372 M → Cfs*4 0.002506 DEL Frame Shift Del COAD
441 R → C 0.004283 SNP Missense Mutation SKCM
522 R → C 0.002294 SNP Missense Mutation OV
572 S → C 0.001764 SNP Missense Mutation LUAD