Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P20645 | M6PR; MPR46; MPRD | Cation-dependent mannose-6-phosphate receptor (CD Man-6-P … | Homo sapiens (Human) | 277 aa |
Protein Details: P20645 (M6PR)
Protein Information
| Accession | P20645 |
|---|---|
| Protein Names | Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46) |
| Gene Symbol | M6PR; MPR46; MPRD |
| Organism | Homo sapiens (Human) |
| Length | 277 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 24357059 26111759 29575903 29733200 31251020 31382980 32651440 32944167 33636221 36430497 37611173 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.567
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
38
LNCaP cells
Specificity: 0.567
38/46 (82.6%)
7
Jurkat T cells
Specificity: 0.104
7/25 (28.0%)
6
HAP1 cells
Specificity: 0.090
6/10 (60.0%)
4
PC3 cells
Specificity: 0.060
4/4 (100.0%)
4
T cells
Specificity: 0.060
4/4 (100.0%)
2
DU145 cells
Specificity: 0.030
2/2 (100.0%)
2
Cerebral cortex
Specificity: 0.030
2/4 (50.0%)
1
U937 cells
Specificity: 0.015
1/1 (100.0%)
1
HeLa cells
Specificity: 0.015
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.015
1/2 (50.0%)
1
Liver membrane
Specificity: 0.015
1/1 (100.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MFPFYSCWRT11GLLLLLLAVA21VRESWQTEEK31TCDLVGEKGK41ESEKELALVK
51-10051RLKPLFNKSF61ESTVGQGSDT71YIYIFRVCRE81AGNHTSGAGL91VQINKSNGKE
101-150101TVVGRLNETH111IFNGSNWIML121IYKGGDEYDN131HCGKEQRRAV141VMISCNRHTL
151-200151ADNFNPVSEE161RGKVQDCFYL171FEMDSSLACS181PEISHLSVGS191ILLVTFASLV
201-250201AVYVVGGFLY211QRLVVGAKGM221EQFPHLAFWQ231DLGNLVADGC241DFVCRSKPRN
251-277251VPAAYRGVGD261DQLGEESEER271DDHLLPM
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 7 | Prediction (High) | - | - |
| 32 | Prediction (Medium) | - | - |
| 145 | Experimental Prediction (Medium) | Mannose-6-phosphate receptor | 19801377 |
| 240 | Experimental Prediction (High) | Mannose-6-phosphate receptor | 37611173 |
| 244 | Experimental Prediction (High) | Mannose-6-phosphate receptor | 37611173 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 256 | R → C | 0.002506 | SNP | Missense Mutation | COAD |