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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P21279 Gnaq Guanine nucleotide-binding protein G(q) subunit … Mus musculus (Mouse) 359 aa

Protein Details: P21279 (Gnaq)

Protein Information
AccessionP21279
Protein NamesGuanine nucleotide-binding protein G(q) subunit alpha (EC 3.6.5.-) (Guanine nucleotide-binding protein alpha-q)
Gene SymbolGnaq
OrganismMus musculus (Mouse)
Length359 aa
IsoformsNo isoforms
Related PMIDs 29217618 29575903 29733200 31772009 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTLESIMACC11LSEEAKEARR21INDEIERQLR31RDKRDARREL41KLLLLGTGES
51-10051GKSTFIKQMR61IIHGSGYSDE71DKRGFTKLVY81QNIFTAMQAM91IRAMDTLKIP
101-150101YKYEHNKAHA111QLVREVDVEK121VSAFENPYVD131AIKSLWNDPG141IQECYDRRRE
151-200151YQLSDSTKYY161LNDLDRVADP171SYLPTQQDVL181RVRVPTTGII191EYPFDLQSVI
201-250201FRMVDVGGQR211SERRKWIHCF221ENVTSIMFLV231ALSEYDQVLV241ESDNENRMEE
251-300251SKALFRTIIT261YPWFQNSSVI271LFLNKKDLLE281EKIMYSHLVD291YFPEYDGPQR
301-350301DAQAAREFIL311KMFVDLNPDS321DKIIYSHFTC331ATDTENIRFV341FAAVKDTILQ
351-359351LNLKEYNLV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
9 SWISSPALM DBPTM CYSMODDB -
Brain (34200797)
Forebrain (28680068)
brain (39008777)
Brain (35358180)
GPS-Palm: 0.89
Deep-Palm: 0.03
10 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
Brain (35358180)
GPS-Palm: 0.89
Deep-Palm: 0.04
144 - -
Brain (35358180)
GPS-Palm: 0.80
Deep-Palm: 0.66
219 - - -
Deep-Palm: 0.76
330 - -
Liver (34884899)
Brain (35358180)
Deep-Palm: 0.16
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.312
5
Liver
Specificity: 0.111
5/5 (100.0%)
4
Raw 264.7
Specificity: 0.089
4/4 (100.0%)
4
Brain
Specificity: 0.089
4/4 (100.0%)
2
Testis
Specificity: 0.044
2/2 (100.0%)
1
NSC
Specificity: 0.022
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.931
27
Brain tissue (Mass)
Specificity: 0.600
27/56 (48.2%)
2
Liver tissue (Mass)
Specificity: 0.044
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine