Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P21854 | CD72 | B-cell differentiation antigen CD72 (Lyb-2) … | Homo sapiens (Human) | 359 aa |
Protein Details: P21854 (CD72)
Protein Information
| Accession | P21854 |
|---|---|
| Protein Names | B-cell differentiation antigen CD72 (Lyb-2) (CD antigen CD72) |
| Gene Symbol | CD72 |
| Organism | Homo sapiens (Human) |
| Length | 359 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAEAITYADL11RFVKAPLKKS21ISSRLGQDPG31ADDDGEITYE41NVQVPAVLGV
51-10051PSSLASSVLG61DKAAVKSEQP71TASWRAVTSP81AVGRILPCRT91TCLRYLLLGL
101-150101LLTCLLLGVT111AICLGVRYLQ121VSQQLQQTNR131VLEVTNSSLR141QQLRLKITQL
151-200151GQSAEDLQGS161RRELAQSQEA171LQVEQRAHQA181AEGQLQACQA191DRQKTKETLQ
201-250201SEEQQRRALE211QKLSNMENRL221KPFFTCGSAD231TCCPSGWIMH241QKSCFYISLT
251-300251SKNWQESQKQ261CETLSSKLAT271FSEIYPQSHS281YYFLNSLLPN291GGSGNSYWTG
301-350301LSSNKDWKLT311DDTQRTRTYA321QSSKCNKVHK331TWSWWTLESE341SCRSSLPYIC
351-359351EMTAFRFPD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 88 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.98
|
|
| 92 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.98
|
|
| 104 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.98
|
|
| 113 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.97
|
|
| 188 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.96
|
|
| 226 | - | - | - |
Deep-Palm: 0.07
|
|
| 232 | - | - | - |
Deep-Palm: 0.04
|
|
| 233 | - | - | - |
Deep-Palm: 0.03
|
|
| 244 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.03
|
|
| 261 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.22
|
|
| 325 | - | - | - |
Deep-Palm: 0.09
|
|
| 342 | - | - | - |
Deep-Palm: 0.14
|
|
| 350 | - | - | - |
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Primary T cell
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 144 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 231 | T → delinsICPFT**YP | 0.001969 | INS | Nonsense Mutation | HNSC |
| 232 | C → Lfs*31 | 0.001969 | INS | Frame Shift Ins | HNSC |
| 298 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 315 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 232* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |