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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P21926 CD9; MIC3; TSPAN29; GIG2 CD9 antigen (5H9 antigen) (Cell … Homo sapiens (Human) 228 aa

Protein Details: P21926 (CD9)

Protein Information
Accession P21926
Protein Names CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene Symbol CD9; MIC3; TSPAN29; GIG2
Organism Homo sapiens (Human)
Length 228 aa
Isoforms No isoforms
Related PMIDs 19801377 22496122 24357059 26111759 26876311 29575903 29733200 31251020 33636221 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.710
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
44
LNCaP cells
Specificity: 0.710
44/46 (95.7%)
4
HAP1 cells
Specificity: 0.065
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.065
4/4 (100.0%)
3
T cells
Specificity: 0.048
3/4 (75.0%)
2
DU145 cells
Specificity: 0.032
2/2 (100.0%)
2
Endothelial cells
Specificity: 0.032
2/2 (100.0%)
1
HeLa cells
Specificity: 0.016
1/1 (100.0%)
1
Prefrontal cortex
Specificity: 0.016
1/1 (100.0%)
1
Liver membrane
Specificity: 0.016
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPVKGGTKCI11KYLLFGFNFI21FWLAGIAVLA31IGLWLRFDSQ41TKSIFEQETN
51-10051NNNSSFYTGV61YILIGAGALM71MLVGFLGCCG81AVQESQCMLG91LFFGFLLVIF
101-150101AIEIAAAIWG111YSHKDEVIKE121VQEFYKDTYN131KLKTKDEPQR141ETLKAIHYAL
151-200151NCCGLAGGVE161QFISDICPKK171DVLETFTVKS181CPDAIKEVFD191NKFHIIGAVG
201-228201IGIAVVMIFG211MIFSMILCCA221IRRNREMV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
9 DBPTM SWISSPALM Prediction (Medium) - -
78 DBPTM SWISSPALM Prediction (Medium) Tetraspanin family -
79 DBPTM SWISSPALM Prediction (Medium) Tetraspanin family -
87 DBPTM SWISSPALM Tetraspanin family -
152 Experimental Prediction (High) - 29575903
153 Experimental Prediction (High) - 29575903
167 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
181 Prediction (Medium) - -
218 DBPTM SWISSPALM Prediction (High) - -
219 DBPTM SWISSPALM Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
12 Y → C 0.002141 SNP Missense Mutation SKCM
222 R → C 0.002506 SNP Missense Mutation COAD
152* C → ? 0.001887 SNP Nonsense Mutation UCEC
78* C → ? 0.001887 SNP Nonsense Mutation UCEC