Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P21926 | CD9 | CD9 antigen (5H9 antigen) (Cell … | Homo sapiens (Human) | 228 aa |
Protein Details: P21926 (CD9)
Protein Information
| Accession | P21926 |
|---|---|
| Protein Names | CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9) |
| Gene Symbol | CD9 |
| Organism | Homo sapiens (Human) |
| Length | 228 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 24357059 26111759 26876311 31251020 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPVKGGTKCI11KYLLFGFNFI21FWLAGIAVLA31IGLWLRFDSQ41TKSIFEQETN
51-10051NNNSSFYTGV61YILIGAGALM71MLVGFLGCCG81AVQESQCMLG91LFFGFLLVIF
101-150101AIEIAAAIWG111YSHKDEVIKE121VQEFYKDTYN131KLKTKDEPQR141ETLKAIHYAL
151-200151NCCGLAGGVE161QFISDICPKK171DVLETFTVKS181CPDAIKEVFD191NKFHIIGAVG
201-228201IGIAVVMIFG211MIFSMILCCA221IRRNREMV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 9 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.02
|
| 78 | DBPTM SWISSPALM | Tetraspanin family | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.97
|
| 79 | DBPTM SWISSPALM | Tetraspanin family | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.97
|
| 87 | DBPTM SWISSPALM | Tetraspanin family | - | - |
Deep-Palm: 0.95
|
| 152 | - |
HeLa
(29575903)
|
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.90
Deep-Palm: 0.97
|
|
| 153 | - |
HeLa
(29575903)
|
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.91
Deep-Palm: 0.97
|
|
| 167 | SWISSPALM DBPTM CYSMODDB | - | - |
LNCaP
(31251020)
cerebral cortex
(36430497)
|
GPS-Palm: 0.83
Deep-Palm: 0.87
|
| 181 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.84
Deep-Palm: 0.73
|
|
| 218 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
| 219 | DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
4
LNCaP
Specificity: 0.211
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.211
4/4 (100.0%)
2
Primary T cell
Specificity: 0.105
2/2 (100.0%)
1
EC cell
Specificity: 0.053
1/1 (100.0%)
1
frontal cortex
Specificity: 0.053
1/1 (100.0%)
1
heart
Specificity: 0.053
1/1 (100.0%)
1
HUVECs
Specificity: 0.053
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Cerebral Cortex (Mass)
Specificity: 0.211
4/4 (100.0%)
1
LNCaP cells (Mass)
Specificity: 0.053
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 12 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 222 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 152* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |
| 78* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |