Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P21981 Tgm2 Protein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) … Mus musculus (Mouse) 686 aa

Protein Details: P21981 (Tgm2)

Protein Information
AccessionP21981
Protein NamesProtein-glutamine gamma-glutamyltransferase 2 (EC 2.3.2.13) (Isopeptidase TGM2) (EC 3.4.-.-) (Protein-glutamine deamidase TGM2) (EC 3.5.1.44) (Protein-glutamine dopaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine histaminyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine noradrenalinyltransferase TGM2) (EC 2.3.1.-) (Protein-glutamine serotonyltransferase TGM2) (EC 2.3.1.-) (Tissue transglutaminase) (tTG) (Transglutaminase II) (TGase II) (Transglutaminase-2) (TG2) (TGase-2) (TGase2)
Gene SymbolTgm2
OrganismMus musculus (Mouse)
Length686 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35477839 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAEELLLERC11DLEIQANGRD21HHTADLCQEK31LVLRRGQRFR41LTLYFEGRGY
51-10051EASVDSLTFG61AVTGPDPSEE71AGTKARFSLS81DNVEEGSWSA91SVLDQQDNVL
101-150101SLQLCTPANA111PIGLYRLSLE121ASTGYQGSSF131VLGHFILLYN141AWCPADDVYL
151-200151DSEEERREYV161LTQQGFIYQG171SVKFIKSVPW181NFGQFEDGIL191DTCLMLLDMN
201-250201PKFLKNRSRD211CSRRSSPIYV221GRVVSAMVNC231NDDQGVLLGR241WDNNYGDGIS
251-300251PMAWIGSVDI261LRRWKEHGCQ271QVKYGQCWVF281AAVACTVLRC291LGIPTRVVTN
301-350301YNSAHDQNSN311LLIEYFRNEF321GELESNKSEM331IWNFHCWVES341WMTRPDLQPG
351-400351YEGWQAIDPT361PQEKSEGTYC371CGPVSVRAIK381EGDLSTKYDA391PFVFAEVNAD
401-450401VVDWIRQEDG411SVLKSINRSL421VVGQKISTKS431VGRDDREDIT441HTYKYPEGSP
451-500451EEREVFTKAN461HLNKLAEKEE471TGVAMRIRVG481DSMSMGNDFD491VFAHIGNDTS
501-550501ETRECRLLLC511ARTVSYNGVL521GPECGTEDIN531LTLDPYSENS541IPLRILYEKY
551-600551SGCLTESNLI561KVRGLLIEPA571ANSYLLAERD581LYLENPEIKI591RVLGEPKQNR
601-650601KLVAEVSLKN611PLSDPLYDCI621FTVEGAGLTK631EQKSVEVSDP641VPAGDLVKAR
651-686651VDLFPTDIGL661HKLVVNFQCD671KLKSVKGYRN681VIIGPA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
10 Immunoglobulin-like fold Immunoglobulin E-set - -
GPS-Palm: 0.67
Deep-Palm: 0.05
27 Immunoglobulin-like fold Immunoglobulin E-set Transglutaminase, N-terminal - -
Deep-Palm: 0.95
105 - - -
GPS-Palm: 0.76
Deep-Palm: 0.93
143 - - -
Deep-Palm: 0.64
193 - - -
Deep-Palm: 0.47
211 - - -
GPS-Palm: 0.77
Deep-Palm: 0.86
230 - - -
Deep-Palm: 0.72
269 - - -
Deep-Palm: 0.15
277 - - -
Deep-Palm: 0.15
285 - - -
GPS-Palm: 0.70
Deep-Palm: 0.67
290 - - -
GPS-Palm: 0.82
Deep-Palm: 0.70
336 - - -
Deep-Palm: 0.05
370 - - -
GPS-Palm: 0.72
Deep-Palm: 0.93
371 - - -
GPS-Palm: 0.84
Deep-Palm: 0.94
505 - - -
GPS-Palm: 0.67
Deep-Palm: 0.44
510 - - -
GPS-Palm: 0.77
Deep-Palm: 0.90
524 - - -
Deep-Palm: 0.76
553 SWISSPALM DBPTM CYSMODDB Transglutaminase family C-terminal ig like domain
Liver (28526873)
-
GPS-Palm: 0.95
Deep-Palm: 0.96
619 SWISSPALM DBPTM CYSMODDB Transglutaminase family C-terminal ig like domain
Liver (28526873)
-
Deep-Palm: 0.97
669 SWISSPALM DBPTM CYSMODDB Transglutaminase family C-terminal ig like domain
Liver (28526873)
-
GPS-Palm: 0.93
Deep-Palm: 0.79
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
6
Liver
Specificity: 0.750
6/6 (100.0%)
2
Testis
Specificity: 0.250
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine