Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P23284 PPIB; CYPB Peptidyl-prolyl cis-trans isomerase B (PPIase … Homo sapiens (Human) 216 aa

Protein Details: P23284 (PPIB)

Protein Information
Accession P23284
Protein Names Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)
Gene Symbol PPIB; CYPB
Organism Homo sapiens (Human)
Length 216 aa
Isoforms No isoforms
Related PMIDs 21076176 26876311 29575903 29733200 31251020 31382980 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.589
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.589
33/46 (71.7%)
10
HAP1 cells
Specificity: 0.179
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.071
4/25 (16.0%)
4
293T cells
Specificity: 0.071
4/10 (40.0%)
3
PC3 cells
Specificity: 0.054
3/4 (75.0%)
1
U937 cells
Specificity: 0.018
1/1 (100.0%)
1
Prefrontal cortex
Specificity: 0.018
1/1 (100.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLRLSERNMK11VLLAAALIAG21SVFFLLLPGP31SAADEKKKGP41KVTVKVYFDL
51-10051RIGDEDVGRV61IFGLFGKTVP71KTVDNFVALA81TGEKGFGYKN91SKFHRVIKDF
101-150101MIQGGDFTRG111DGTGGKSIYG121ERFPDENFKL131KHYGPGWVSM141ANAGKDTNGS
151-200151QFFITTVKTA161WLDGKHVVFG171KVLEGMEVVR181KVESTKTDSR191DKPLKDVIIA
201-216201DCGKIEVEKP211FAIAKE
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
202 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) - 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
5 S → Cfs*31 0.002141 INS Frame Shift Ins SKCM
95 R → C 0.002506 SNP Missense Mutation COAD
95 R → C 0.005435 SNP Missense Mutation ESCA
133 Y → C 0.001969 SNP Missense Mutation HNSC