Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P23492 Pnp Purine nucleoside phosphorylase (PNP) (EC … Mus musculus (Mouse) 289 aa

Protein Details: P23492 (Pnp)

Protein Information
AccessionP23492
Protein NamesPurine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
Gene SymbolPnp
OrganismMus musculus (Mouse)
Length289 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MENEFTYEDY11ETTAKWLLQH21TEYRPQVAVI31CGSGLGGLTA41HLKEAQIFDY
51-10051NEIPNFPQST61VQGHAGRLVF71GLLNGRCCVM81MQGRFHMYEG91YSLSKVTFPV
101-150101RVFHLLGVET111LVVTNAAGGL121NPNFEVGDIM131LIRDHINLPG141FCGQNPLRGP
151-200151NDERFGVRFP161AMSDAYDRDM171RQKAFTAWKQ181MGEQRKLQEG191TYVMLAGPNF
201-250201ETVAESRLLK211MLGADAVGMS221TVPEVIVARH231CGLRVFGFSL241ITNKVVMDYE
251-289251NLEKANHMEV261LDAGKAAAQT271LERFVSILME281SIPLPDRGS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
31 Nucleoside phosphorylase superfamily Purine nucleoside phosphorylase - -
Deep-Palm: 0.96
77 - - -
GPS-Palm: 0.77
Deep-Palm: 0.71
78 - - -
GPS-Palm: 0.71
Deep-Palm: 0.49
142 SWISSPALM DBPTM CYSMODDB Phosphorylase superfamily
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.79
Deep-Palm: 0.64
231 - - -
GPS-Palm: 0.74
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.714
5
Liver
Specificity: 0.385
5/5 (100.0%)
2
Testis
Specificity: 0.154
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.462
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine